SELENITE, SODIUM

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Mallard duck (Anas platyrhynchos)

Citation:

Embryotoxic and teratogenic effects of selenium in the diet of mallards

Author(s)
Hoffman, David J. and Gary H. Heinz
Pages
477-490
Year
Volume
24
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
SELENITE, SODIUM, SELENOMETHIONINE decreased @ 25 ppm (selenite), 10 ppm (selenomethionine) hatchability compared to controls Not Reported Juvenile 5-11 pairs/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE increased @ 5, 10, 25 ppm (as selenite), 10 ppm (as selenomethionine) plasma glutathione peroxidase activity in hatchlings compared to controls Not Reported Juvenile 5-11 pairs/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE increased @ 25 ppm plasma uric acid concentration in hatchlings versus controls Not Reported Juvenile 5-11 pairs/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE increased @ 10,25 ppm (as selenite), 10 ppm (as selenomethionine) number of embryos showing malformations or embryotoxicity compared to controls Not Reported Embryo 5-11 pairs/group Toxicity Factor Datasets Laboratory
Citation:

Subchronic effects of sodium selenite and selenomethionine on several immune functions in mallards.

Author(s)
Fairbrother, A. and J. Fowles
Pages
836-844
Year
Volume
19
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
SELENITE, SODIUM, SELENOMETHIONINE increased @ 3.5 mg/L (selenite) or 2.2 mg/L (selenomethionine) serum ALT enzyme activity versus controls n high selenite and selenomethionine groups. Male Adult Controls = 24
Treated = 8 		laboratory Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE decreased blood monocyte counts after 78 days exposure versus controls Male Adult Controls = 24
Treated = 8 		Laboratory Toxicity Factor Datasets Laboratory
Citation:

Kinetics of selenium incorporation into tissues of female mallard ducks

Author(s)
Wilson, David S., Peng Zhang, Rong He, Ron Ota, Stanley T. Omaye
Pages
51-60
Year
Volume
122
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
SELENITE, SODIUM figure/table figures and tables of selenium concentration over time (% of administered dose) Female Adult Not Reported Toxicity Factor Datasets Laboratory
Citation:

Toxicity of organic and inorganic selenium to mallard ducklings

Author(s)
Heinz, G.H., D.J. Hoffman and L.G. Gold
Pages
561-568
Year
Volume
17
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
SELENITE, SODIUM 18(4.8) ppm, wet wt @ 40 ppm; 6.9(2.07) ppm, wet wt @ 80 ppm mean liver concentrations (SE) in ducklings fed selenite that died Not Reported Juvenile 40 birds/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE no effect tarsus length, 10th primary length, heart weight versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE increased @ 40, 80 ppm selenite or selenomethionine duckling mortality versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE decreased (liver decreased with selenite only) bw and liver wt versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets Laboratory
SELENITE, SODIUM, SELENOMETHIONINE decreased food consumption versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets Laboratory
Citation:

Hepatic glutathione metabolism and lipid peroxidation in response to excess dietary selenomethionine and selenite in mallard ducklings

Author(s)
Hoffman, David J., Gary H. Heinz and Alexander J. Krynitsky
Pages
263-271
Year
Volume
27
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
SELENITE, SODIUM increased @ 40 ppm (12.5%) mortality compared to controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
SELENITE, SODIUM increased to 0.4 (@ 0 ppm), 5.0 (@ 10 ppm), 3.2 (@ 20 ppm), 2.8 (@ 40 ppm) ppm, wet wt Se concentrations in livers after 6 wks of treatment versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
SELENITE, SODIUM increased @ 20, 40 ppm hepatic protein concentrations versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
SELENITE, SODIUM increased @ 40 ppm hepatic malondialdehyde concentrations versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
SELENITE, SODIUM increased @ 10,20,40 ppm incidence of altered hepatic glutathione metabolism versus controls Not Reported Juvenile 40 birds/group Toxicity Factor Datasets day old Laboratory
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OEHHA California Office of Environmental Health Hazard Assessment