BORIC ACID

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Mallard duck (Anas platyrhynchos)

Citation:

Effects of boron on growth and physiology in mallard ducklings

Author(s)
Hoffman, David J., Michael B. Camardese, Leonard J. Lecaptain
Pages
335-346
Year
Volume
9
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
BORIC ACID 2 ug/g @ control; 4 ug/g @ 100 ppm; 5 ug/g @ 400 ppm; 51 ug/g @ 1600 ppm boron accumulation in brain (geometric mean; ug/g dry weight) Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
BORIC ACID decrease @ 400 and 1600 ppm brain ATP (nmol/g) and protein (mg/g) concentrations Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
BORIC ACID 1 ug/g @ controls; 3 ug/g @ 100 ppm; 3 ug/g @ 400 ppm; 29 ug/g @ 1600 ppm liver boron concentration (geometric mean; ug/g dry weight) Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
BORIC ACID decrease @ 1600 ppm growth rate measured as changes in body weight, compared to control Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
BORIC ACID decrease @ 1600 ppm hematocrit and hemoglobin concentration, compared to controls Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
BORIC ACID increase @ 100, 400, 1600 ppm plasma triglyceride concentration (21-42% increase, compared to controls) Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
BORIC ACID increase @ 1600 ppm plasma calcium concentration (6-10% greater than controls) and brain acetylcholinestrase activity (umol/min/g) Both Male and Female Juvenile 10 animals/pen; 3 pens/dose Toxicity Factor Datasets 1 d Laboratory
Citation:

Effects of boron and selenium on mallard reproduction and duckling growth and survival

Author(s)
Stanley, Thomas R., Jr., Gregory J. Smith, David J. Hoffman, Gary H. Heinz, and Roger Rosscoe
Pages
1124-1132
Year
Issue
7
Volume
15
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
BORIC ACID, SELENOMETHIONINE no effect due to added Se liver weight, hemoglobin concentrations, hematocrit versus controls Both Male and Female Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE no effect due to added Se onset of egg laying, eggshell thickness, egg weight, egg fertility, embryo deformities versus controls Both Male and Female Both Adults and Juveniles 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 7 ppm Se hatching success versus controls Female Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 900 ppm B total SH, liver protein, sorbitol dehyrogenase versus controls Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 900 ppm B body weight and growth at 0, 7,and 14 days post-hatch versus controls Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 7 ppm Se body weight and weight gain at 7 and 14 days post-hatch versus 3.5 ppm Se group Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE increased @ 3.5 ppm Se survival between 7 and 14 days post-hatch versus controls Both Male and Female Juvenile 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 7 ppm duckling production versus 3.5 ppm Se group Both Male and Female Both Adults and Juveniles 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE 4.6 (0.18) ppm B @ 450 ppm B; 8.5 (0.34) ppm B @ 900 ppm B; 3.7 (0.16) ppm Se @ 3.5 ppm Se; 6.2 (0.27) ppm Se @ 7 ppm mean (SE) wet wt concentrations of B and Se in liver Both Male and Female Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE 6.5 (0.25) ppm B @ 450 ppm B; 11 (0.4) ppm B @ 900 ppm B; 3.5 (0.10) ppm Se @ 3.5 ppm Se; 7.1 (0.28) ppm Se @ 7 ppm mean (SE) wet wt concentrations of B and Se in egg Both Male and Female Both Adults and Juveniles 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 900 ppm B body weight versus controls Both Male and Female Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 900 ppm B liver weight versus 450 ppm B group Male Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 900 ppm B hemoglobin concentrations versus controls Male Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE no effect onset of egg laying, eggshell thickness, frequency of embryo deformities versus controls Both Male and Female Both Adults and Juveniles 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 900 ppm B egg weight, hatching success, egg fertility versus controls Both Male and Female Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
BORIC ACID, SELENOMETHIONINE reduced @ 7 ppm Se body weight versus controls Female Adult 14 pairs/treatment Toxicity Factor Datasets 1 yr Laboratory
Citation:

Interactive effects of boron, selenium, and dietary protein on survival, growth, and physiology in mallard ducklings

Author(s)
Hoffman, David J., Caroline J. Sanderson, Leonard J. LeCaptain, Eugene Cromartie and Grey W. Pendleton
Pages
288-294
Year
Volume
20
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
BORIC ACID, SELENOMETHIONINE decreased @ 60 ppm Se (47% mort.) survival versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 60 ppm Se body, liver, and spleen weight; tarsus length versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 60 ppm Se (100% mort.) survival versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 15 ppm Se body, liver, and spleen weight; tarsus length versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE increased @ 15, 60 ppm Se (with and w/out B), 1000 ppm B incidence of plasma chemistry changes versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE increased @ 15 ppm Se (with and w/out B), 1000 ppm B incidence of plasma chemistry changes versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 1000 ppm B hematocrits and hemoglobin concentrations versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE decreased @ 15 ppm Se (with or w/out B), and 1000 ppm B hematocrits and hemoglobin concentrations versus controls Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE 10.8 (@ 15 ppm Se), 56.0 (@ 60 ppm) ppm Se, wet wt
11.0 (@ 1000 ppm B) ppm B, wet wt 		geometric mean Se and B concentrations in liver Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
BORIC ACID, SELENOMETHIONINE 22.5 (@ 15 ppm Se w/out B), 41.9 (@ 15 ppm Se w/B) ppm Se, wet wt
13.0 (@ 1000 ppm B) ppm B, wet wt 		geometric mean Se and B concentrations in liver Not Reported Juvenile 15 birds/group Toxicity Factor Datasets day old Laboratory
Citation:

Toxic effects of boron on mallard reproduction

Author(s)
Smith, Gregory J. and Velora P. Anders
Pages
943-950
Year
Volume
8
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
BORIC ACID decrease @ 1000 ppm % hatching success in fertile eggs and productivity per female (mean # of 21 d old ducklings) Both Male and Female Adult 15/sex/dose Toxicity Factor Datasets Laboratory
BORIC ACID no effect eggshell thickness and Ratcliffe index of eggshell quality Female Adult 15/dose Toxicity Factor Datasets Laboratory
BORIC ACID increase @ 1000 ppm % embryo mortality (day 15 to hatch) and duckling mortality (hatch to day 7) Both Male and Female Both Adults and Juveniles 11-23/dose Toxicity Factor Datasets Laboratory
BORIC ACID decrease @ 300, 1000 ppm body weight of hatchlings, compared to controls Both Male and Female Hatchling 11-23/dose Toxicity Factor Datasets Laboratory
BORIC ACID decrease @ 30, 300, 1000 ppm hatchling weight gain over 21 d, compared to controls Both Male and Female Hatchling 11-23/dose Toxicity Factor Datasets Laboratory
BORIC ACID Egg; 3 ug/g @ 30 ppm, 13 ug/g @ 300 ppm, 49 ug/g @ 1000 ppm: Liver; 15 ug/g @ 300 ppm, 33 ug/g @ 1000 ppm: Brain; 14 ug/g @ 300 ppm, 41 ug/g @ 1000 ppm boron concentrations in adult tissues (geometric mean; ug/g dry weight). Both Male and Female Adult 10-20/dose Toxicity Factor Datasets Laboratory
BORIC ACID Liver; 3 ug/g @ 30 ppm, 17 ug/g @ 300 ppm, 51 ug/g @ 1000 ppm: Brain; 4 ug/g @ 30 ppm, 19 ug/g @ 300 ppm, 66 ug/g @ 1000 ppm boron concentrations in ducklings 21 d of age (geometric mean; ug/g dry weight). Concentrations at other doses were not detected. Both Male and Female Juvenile 10-13/dose Toxicity Factor Datasets Laboratory
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