| Chemical | Toxicity Endpoint Type | Endpoint Description | Endpoint Value | Sample Size | Life Cycle Stage | Study Duration | Type |
|---|---|---|---|---|---|---|---|
| BORIC ACID | TOX-Non-Repro-Sublethal - whole animal | growth rate measured as changes in body weight, compared to control | decrease @ 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
| BORIC ACID | TOX-Non-Repro-Sublethal - cellular/biochemical effects | hematocrit and hemoglobin concentration, compared to controls | decrease @ 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
| BORIC ACID | TOX-Non-Repro-Sublethal - cellular/biochemical effects | plasma triglyceride concentration (21-42% increase, compared to controls) | increase @ 100, 400, 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
| BORIC ACID | TOX-Non-Repro-Sublethal - cellular/biochemical effects | plasma calcium concentration (6-10% greater than controls) and brain acetylcholinestrase activity (umol/min/g) | increase @ 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
| BORIC ACID | TOX-EXP IND - accumulation | boron accumulation in brain (geometric mean; ug/g dry weight) | 2 ug/g @ control; 4 ug/g @ 100 ppm; 5 ug/g @ 400 ppm; 51 ug/g @ 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
| BORIC ACID | TOX-Non-Repro-Sublethal - cellular/biochemical effects | brain ATP (nmol/g) and protein (mg/g) concentrations | decrease @ 400 and 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
| BORIC ACID | TOX-Non-Repro-Sublethal - cellular/biochemical effects | liver boron concentration (geometric mean; ug/g dry weight) | 1 ug/g @ controls; 3 ug/g @ 100 ppm; 3 ug/g @ 400 ppm; 29 ug/g @ 1600 ppm | 10 animals/pen; 3 pens/dose | Juvenile | 10 wks | Toxicity Factor Datasets |
