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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
BENTAZON | 4530 mg/L | LC50 | NR | Tadpole | Experimental Frog Farm, São Paulo | 6 | 600, 1200, 2400, 4800, 9600 mg/L | TOX-MORT - toxicity benchmarks | 96 hr | Waterborne | Toxicity Factor Datasets |
PENOXSULAM | 7.52 mg/L | LC50 | NR | Tadpole | Experimental Frog Farm, São Paulo | 6 | (+ vegetable oil adjuvant): 2.88 + 55.80; 4.32 + 83.70; 5.76 + 111.60; 7.20 mg/L C 139.50; 8.64 + 167.40 | TOX-MORT - toxicity benchmarks | 96 hr | Waterborne | Toxicity Factor Datasets |
81.57 mg/L | LC50 | NR | Tadpole | Experimental Frog Farm, São Paulo | 6 | Vegetable oil: 55.80; 83.70; 111.60; 139.50; 167.40 mg/L | TOX-MORT - toxicity benchmarks | 96 hr | Waterborne | Toxicity Factor Datasets | |
PERMETHRIN | 0.10 mg/L | LC50 | NR | Tadpole | Experimental Frog Farm, São Paulo | 6 | 0.01, 0.03, 0.09, 0.27, 0.81 mg/L | TOX-MORT - toxicity benchmarks | 96 hr | Waterborne | Toxicity Factor Datasets |
LIDOCAINE | no effect | Heart rate | NR | Adult | 10 | 5 mg/kg (4 mg/mL) | TOX-Non-Repro-Sublethal - whole animal | 60 min | Subcutaneous injection | Toxicity Factor Datasets | |
LIDOCAINE | no effect | Reflexes | NR | Adult | 10 | 5 mg/kg (4 mg/mL) | TOX-Non-Repro-Sublethal - whole animal | 60 min | Subcutaneous injection | Toxicity Factor Datasets | |
LIDOCAINE | 87 ± 17 breaths/min | Reduced gular respiratory rate | NR | Adult | 10 | 5 mg/kg (4 mg/mL) | TOX-Non-Repro-Sublethal - whole animal | 60 min | Subcutaneous injection | Toxicity Factor Datasets | |
LIDOCAINE | See citation Figure 3 | Heart rate | NR | Adult | 6 | 5 mg/kg (4 mg/mL) | TOX-Non-Repro-Sublethal - whole animal | 80 min | Subcutaneous injection following sedation, surgery, recovery | Toxicity Factor Datasets | |
LIDOCAINE | See citation Figure 3 | Mean arterial pressure | NR | Adult | 6 | 5 mg/kg (4 mg/mL) | TOX-Non-Repro-Sublethal - whole animal | 80 min | Subcutaneous injection following sedation, surgery, recovery | Toxicity Factor Datasets | |
LIDOCAINE | See citation Figure 3 | Mean arterial pressure | NR | Adult | 6 | 50 mg/kg (20 mg/mL) | TOX-Non-Repro-Sublethal - whole animal | 160 min | Subcutaneous injection following sedation, surgery, recovery | Toxicity Factor Datasets | |
DIPHACINONE | 0.333 | % metabolism by liver microsome | M | Not Reported | Castroville, CA | 14 | NR | TOX-Non-Repro-Sublethal - cellular/biochemical effects | NR | Environmental | Toxicity Factor Datasets |
TETRODOTOXIN | 45.9 | % speed reduction | B | Neonate | Benton County | 25 | 0.001 mg | TOX-Non-Repro-Sublethal - behavioral effects | Single | Intraperitoneal injection | Toxicity Factor Datasets |
TETRODOTOXIN | 54.7 | % speed reduction | B | Neonate | Benton County | 25 | 0.04 mg | TOX-Non-Repro-Sublethal - behavioral effects | Single | Oral | Toxicity Factor Datasets |
TETRODOTOXIN | 71.6 | % speed reduction | B | Neonate | Benton County | 25 | 0.04 mg | TOX-Non-Repro-Sublethal - behavioral effects | Single | Oral | Toxicity Factor Datasets |
TETRODOTOXIN | 62.6 | % speed reduction | B | Neonate | Bear Lake County | 17 | 0.00005 mg | TOX-Non-Repro-Sublethal - behavioral effects | Single | Intraperitoneal injection | Toxicity Factor Datasets |
TETRODOTOXIN | 71.7 | % speed reduction | B | Neonate | Bear Lake County | 17 | 0.002 mg | TOX-Non-Repro-Sublethal - behavioral effects | Single | Oral | Toxicity Factor Datasets |
TETRODOTOXIN | 85.8 | % speed reduction | B | Neonate | Bear Lake County | 17 | 0.002 mg | TOX-Non-Repro-Sublethal - behavioral effects | Single | Oral | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
ATRAZINE | No effect | Mortality | B | Neonate | Eggs from Lincoln County, MT | 80 | 0, 1.84, 18.4, 184 µg/L | TOX-MORT - dose-response data | 30 d | Waterborne | Toxicity Factor Datasets |
ATRAZINE | See citation Figure 1A | Larval period (d) | B | Embryo | Eggs from Lincoln County, MT | 80 | 0, 1.84, 18.4, 184 µg/L | TOX-REPRO - development | 30 d | Waterborne | Toxicity Factor Datasets |
ATRAZINE | See citation Figure 1B | Mass at metamorphosis (mg) | B | Embryo | Eggs from Lincoln County, MT | 80 | 0, 1.84, 18.4, 184 µg/L | TOX-Non-Repro-Sublethal - whole animal | 30 d | Waterborne | Toxicity Factor Datasets |
ATRAZINE | See citaiton Figure 1C | Body size at metamorphosis | B | Embryo | Eggs from Lincoln County, MT | 80 | 0, 1.84, 18.4, 184 µg/L | TOX-Non-Repro-Sublethal - whole animal | 30 d | Waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | No effect | Susceptibility to predation | B | Neonate | Eggs from local breeding pond | 10 | 0, 0.01, 0.1, 1.0, 10.0 mg/L | TOX-Non-Repro-Sublethal - indirect effects | See citation | Waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | See citation Table 1 | % hatch | B | Embryo | Eggs from local breeding pond | 90-132 | 0, 0.01, 0.1, 1.0, 10.0 mg/L | TOX-REPRO - reproductive success | See citation | Waterborne | Toxicity Factor Datasets |
NITRATE, SODIUM | No effect | % survival | NR | Embryo | Willamette Valley, OR | 10 | 0, 5, 20 mg/L | TOX-MORT - toxicity benchmarks | 3 w | Waterborne | Toxicity Factor Datasets |
NITRATE, SODIUM | No effect | Embryo mass | NR | Embryo | Willamette Valley, OR | 10 | 0, 5, 20 mg/L | TOX-Non-Repro-Sublethal - whole animal | 3 w | Waterborne | Toxicity Factor Datasets |
NITRATE, SODIUM | No effect | % survival | NR | Embryo | Cascade Mountain, OR | 10 | 0, 10 mg/L | TOX-MORT - toxicity benchmarks | 3 w | Waterborne | Toxicity Factor Datasets |
NITRATE, SODIUM | No effect | Embryo mass | NR | Embryo | Cascade Mountain, OR | 10 | 0, 10 mg/L | TOX-Non-Repro-Sublethal - whole animal | 3 w | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 2.7 [1.7-3.7 (84% CI)] ppb | LC10 | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 4 d | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 21.4 [17.0-27.0 (84%CI)] ppb | LC50 | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 4 d | Waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
ENDOSULFAN | 172 [117-283 (84% CI)] ppb | LC90 | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 4 d | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 7 ppb | LOEC | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 4 d | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 1.7 [1.1-2.4 (84% CI)] ppb | LC10 | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 8 d | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 13.9 [11.1-17.5 (84% CI)] ppb | LC50 | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 8 d | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 114 [79.0-187 (84% CI)] ppb | LC90 | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 8 d | Waterborne | Toxicity Factor Datasets |
ENDOSULFAN | 7 | LOEC | NR | Embryo | Pymatuning Laboratory of Ecology, Pittsburgh, PA | 10 | 2, 6, 7, 35, 60, 296 ppb | TOX-MORT - toxicity benchmarks | 8 d | Waterborne | Toxicity Factor Datasets |
NITRATE, SODIUM | No effect | % survival | NR | Embryo | Oregon State University, Corvallis | 10 | 0, 5, 20 mg/L | TOX-MORT - toxicity benchmarks | 7 d | Waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
CYPERMETHRIN | No effect | % survival | NR | Embryo | Oregon State University, Corvallis | 10 | 0.0, 1.0, 5.0 µg/L | TOX-MORT - toxicity benchmarks | 48 h | Waterborne | Toxicity Factor Datasets |
CYPERMETHRIN | 0.025 ± 0.003 SE | Embryo mass | NR | Embryo | Oregon State University, Corvallis | 10 | 5.0 µg/L | TOX-Non-Repro-Sublethal - whole animal | 48 h | Waterborne | Toxicity Factor Datasets |
CYPERMETHRIN | 0.269 ± 0.006 SE | Mass | NR | Neonate | Oregon State University, Corvallis | 10 | 0.0 µg/L | TOX-Non-Repro-Sublethal - whole animal | 48 h | Waterborne | Toxicity Factor Datasets |
CYPERMETHRIN | 0.082 ± 0.007 SE | Mass | NR | Neonate | Oregon State University, Corvallis | 10 | 0.5 µg/L | TOX-Non-Repro-Sublethal - whole animal | 48 h | Waterborne | Toxicity Factor Datasets |