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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (2,4'-) | Lipid weight: 151.7, wet: 48.6 ppm | Brown fat concentration | M | Adult | Round Top Mountain, Washington County | 4 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets |
DDE (2,4'-) | Lipid weight: 123.8, wet: 107.5 ppm | White fat concentration, small | M | Adult | Round Top Mountain, Washington County | 4 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets |
DDE (2,4'-) | Lipid weight: 167.2, wet: 150.2 ppm | White fat concentration, large | M | Adult | Round Top Mountain, Washington County | 4 | NR | TOX-EXP IND - accumulation | Environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|
DDE (2,4'-) | 540 ppm | Min. lethal brain concentration | B | Both Adults and Juveniles | NR | TOX-EXP IND - accumulation | Dietary | Toxicity Factor Datasets |
DDE (2,4'-) | 79,000 ppm | Est. min. lethal carcass lipid concentration | B | Both Adults and Juveniles | NR | TOX-EXP IND - accumulation | Dietary | Toxicity Factor Datasets |
DDT (2,4'-) | 12 ppm | Min. lethal brain concentration | B | Both Adults and Juveniles | NR | TOX-EXP IND - accumulation | Dietary | Toxicity Factor Datasets |
DDT (2,4'-) | 470 ppm | Est. min. lethal carcass lipid concentration | B | Both Adults and Juveniles | NR | TOX-EXP IND - accumulation | Dietary | Toxicity Factor Datasets |
Endpoint Value | Toxicity Endpoint Type | Type |
---|---|---|
39 | TOX-MORT - dose-response data | Toxicity Factor Datasets |
LD50=0.9 mg/kg | TOX-MORT - toxicity benchmarks | Toxicity Factor Datasets |
88% reduction in mean body wt. @ 7 ppm in food | TOX-POP - size effects | Toxicity Factor Datasets |
Endpoint Value | Endpoint Description | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|
increase and decrease (inconclusive) | adult sex ratios | Maple Ridge, BC | 591 | 2.2 kg/ha | TOX-POP - size effects | NR | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | Not Reported | Tadpole | 15 animals/group | 0, 25, 50,100, 200, 1000 ug/kg body weight | TOX-MORT - dose-response data | single | intraperitoneal | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | incidence of morphological abnormalities | Not Reported | Tadpole | 15 animals/group | 0, 25, 50,100, 200, 1000 ug/kg body weight | TOX-REPRO - development | single | intraperitoneal | Toxicity Factor Datasets |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | Both Male and Female | Adult | 5 animals/group | 0, 25, 50,100, 250, 500 ug/kg body weight | TOX-MORT - dose-response data | single | intraperitoneal | Toxicity Factor Datasets | |
TETRACHLORODIBENZO-P-DIOXIN (2,3,7,8-) | no effect | histopathological changes in liver, kidney, lung, heart and gonads | Both Male and Female | Adult | 5 animals/group | 0, 25, 50,100, 250, 500 ug/kg body weight | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | intraperitoneal | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FENITROTHION | no effect | hatching success | Not Reported | Embryo | 20 animals/replicate; 3 replicates/dose | 0.5, 1.0, 2.0, 4.0, 8.0 mg/l (nominal) | TOX-REPRO - reproductive success | 24 hr | waterborne | Toxicity Factor Datasets |
FENITROTHION | no effect | avoidance response assessed by daily prodding of newly hatched tadpoles | Not Reported | Embryo | 20 animals/replicate; 3 replicates/dose | 0.5, 1.0, 2.0, 4.0, 8.0 mg/l (nominal) | TOX-REPRO - behavior | 24 hr | waterborne | Toxicity Factor Datasets |
TRICLOPYR | no effect | hatching success | Not Reported | Embryo | 20 animals/replicate; 3 replicates/dose | 0.6, 1.2, 2.4, 4.8 mg/l (nominal) | TOX-REPRO - reproductive success | 48 hr | waterborne | Toxicity Factor Datasets |
TRICLOPYR | no effect | avoidance response assessed by daily prodding of newly hatched tadpoles | Not Reported | Embryo | 20 animals/replicate; 3 replicates/dose | 0.6, 1.2, 2.4, 4.8 mg/l (nominal) | TOX-REPRO - behavior | 48 hr | waterborne | Toxicity Factor Datasets |
HEXAZINONE | no effect | hatching success | Not Reported | Embryo | 20 animals/replicate; 3 replicates/dose | 100 mg/l (nominal) | TOX-REPRO - reproductive success | 8 d | waterborne | Toxicity Factor Datasets |
HEXAZINONE | no effect | Not Reported | Tadpole | 10 animals/replicate; 3 replicates/dose | 100 mg/l (nominal) | TOX-MORT - dose-response data | 9 d | waterborne | Toxicity Factor Datasets | |
TRICLOPYR | increase at 2.4 and 4.8 mg/l | Not Reported | Tadpole | 10 animals/replicate; 3 replicates/dose | 0.6, 1.2, 2.4, 4.8 mg/l (nominal) | TOX-MORT - dose-response data | 48 hr | waterborne | Toxicity Factor Datasets | |
TRICLOPYR | decrease response at 1.2 mg/l | avoidance response assessed by daily prodding | Not Reported | Tadpole | 10 animals/replicate; 3 replicates/dose | 0.6, 1.2, 2.4, 4.8 mg/l (nominal) | TOX-REPRO - behavior | 48 hr | waterborne | Toxicity Factor Datasets |
FENITROTHION | decrease response at 0.5 - 8 mg/l | avoidance response assessed by daily prodding | Not Reported | Tadpole | 10 animals/replicate; 3 replicates/dose | 0.5, 1.0, 2.0, 4.0, 8.0 mg/l (nominal) | TOX-REPRO - behavior | 24 hr | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|
FENITROTHION | increase at 9 mg/l | Not Reported | Tadpole | 10/replicate; 3 replicates/dose | 1, 2, 5, 9 mg/l (nominal) | TOX-MORT - dose-response data | 24 hr | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
GLYPHOSATE | decrease | number of hardwood trees in study area | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 1 study area | 2.2 kg/ha | TOX-Non-Repro-Sublethal - indirect effects | NR | field application | Toxicity Factor Datasets |
GLYPHOSATE | no effect | proportion of trapped animals in breeding condition | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 151 | 2.2 kg/ha | TOX-REPRO - physiology | NR | field application | Toxicity Factor Datasets |
GLYPHOSATE | increase | survival over summer and winter | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 545 | 2.2 kg/ha | TOX-MORT - mortality in the field | NR | field application | Toxicity Factor Datasets |
GLYPHOSATE | no effect | juvenile growth rate (summer and fall) | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 283 | 2.2 kg/ha | TOX-REPRO - physiology | NR | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
GLYPHOSATE | 0.29 | relative density (vs. control) in sprayed area | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-POP - size effects | field application | Toxicity Factor Datasets |
GLYPHOSATE | decrease | percent vegetation cover (vs control) in study area | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-Non-Repro-Sublethal - indirect effects | field application | Toxicity Factor Datasets |
GLYPHOSATE | no effect | adult sex ratios | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-POP - size effects | field application | Toxicity Factor Datasets |
GLYPHOSATE | no effect | age structure as indicated by number of juveniles trapped | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-POP - age distribution effects | field application | Toxicity Factor Datasets |
GLYPHOSATE | increase | mean number of foeti in trapped females | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-REPRO - reproductive success | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLOROCHOLINE CHLORIDE | increase @ 1, 20, 80 mg/kg bw/d | liver weight to bw ratio | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | diet | Toxicity Factor Datasets |
CHLOROCHOLINE CHLORIDE | increase @ 1-80 mg/kg | thymus weight to bw ratios | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | Diet | Toxicity Factor Datasets |
CHLOROCHOLINE CHLORIDE | increase @ 80 mg/kg bw/d | white blood cell counts | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
CHLOROCHOLINE CHLORIDE | increase @ 80 mg/kg bw/d | plaque forming cells/g spleen | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
CHLOROCHOLINE CHLORIDE | decrease @ 80 mg/kg bw/d | reciprocal of hemolysin titers (against sheep rbc) | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
GLYPHOSATE | increase @ 20, 80 mg/kg bw/d | liver weight to body weight ratio | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | Diet | Toxicity Factor Datasets |