PBDE MIXTURE |
See citation |
Thyroid hormones/glandular structure |
NR |
Nestling |
|
57 |
Midway incubation: 1500 ng/g; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Decreased |
Vitamin A homologues |
NR |
Nestling |
|
57 |
Midway incubation: 1500 ng/g; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
See citation |
Oxidative stress |
NR |
Nestling |
|
57 |
Midway incubation: 1500 ng/g; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
86.09 ± 8.40 |
Nestling concentration, whole body |
NR |
Nestling |
|
12 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-EXP IND - accumulation |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Body mass, 21 d |
F |
Nestling |
|
7 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Body mass, 27 d |
F |
Nestling |
|
7 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Growth rate |
F |
Nestling |
|
7 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Body mass, 21 d |
M |
Nestling |
|
5 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Body mass, 27 d |
M |
Nestling |
|
5 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Growth rate |
M |
Nestling |
|
5 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Tarsometatarsus asymptotic length, 21 d |
NR |
Nestling |
|
12 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Tarsometatarsus asymptotic length, 27 d |
NR |
Nestling |
|
12 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Ninth primary feathers, 21 d |
NR |
Nestling |
|
12 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE MIXTURE |
Increased |
Ninth primary feathers, 27 d |
NR |
Nestling |
|
12 |
Midway incubation: 1.5 ppm; Hatch through 29 d: 15.6 ng/g bird/day |
TOX-REPRO - development |
Midway through incubation; 0-29 d post hatch |
In ovo; oral gavage |
Toxicity Factor Datasets |
PBDE TECHNICAL MIXTURE, DE-71 |
288.60 ± 33.35 ng/g |
Egg concentrations |
NR |
Embryo |
Avian Science and Conservation Centre of
McGill University |
17 |
In ovo 1.6 ppm per day parent diet |
TOX-EXP IND - accumulation |
3 w before pairing through 75 d incubation |
In ovo |
Toxicity Factor Datasets |
PBDE TECHNICAL MIXTURE, DE-71 |
1130.59 ± 95.34 ng/g |
Egg concentrations |
NR |
Embryo |
Avian Science and Conservation Centre of
McGill University |
16 |
In ovo 0.3 ppm per day parent diet |
TOX-EXP IND - accumulation |
3 w before pairing through 75 d incubation |
In ovo |
Toxicity Factor Datasets |
PBDE TECHNICAL MIXTURE, DE-71 |
See citation |
Copulation frequency |
B |
Adult |
Avian Science and Conservation Centre of
McGill University |
31 pairs |
0, 1.6, 0.3 ppm per day |
TOX-REPRO - behavior |
3 w before pairing through 75 d incubation |
Dietary |
Toxicity Factor Datasets |
PBDE TECHNICAL MIXTURE, DE-71 |
See citation |
Nest box inspection by males |
M |
Adult |
Avian Science and Conservation Centre of
McGill University |
31 pairs |
0, 1.6, 0.3 ppm per day |
TOX-REPRO - behavior |
3 w before pairing through 75 d incubation |
Dietary |
Toxicity Factor Datasets |
PBDE TECHNICAL MIXTURE, DE-71 |
See citation |
Food intake |
B |
Adult |
Avian Science and Conservation Centre of
McGill University |
31 pairs |
0, 1.6, 0.3 ppm per day |
TOX-REPRO - behavior |
3 w before pairing through 75 d incubation |
Dietary |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
Increased |
Egg concentrations |
NR |
Embryo |
|
28 |
In ovo, 0.51 µg/g body weight/d parent diet |
TOX-EXP IND - accumulation |
Through hatching |
In ovo |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
Decreased |
Second clutch |
B |
Adult |
|
29 |
0.51 µg/g body weight/d from pairing-hatching |
TOX-REPRO - reproductive success |
Through hatching |
Dietary |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
Decreased |
Timing of laying |
B |
Adult |
|
29 |
0.51 µg/g body weight/d from pairing-hatching |
TOX-REPRO - behavior |
Through hatching |
Dietary |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
Increased |
Clutch size |
NR |
Adult |
|
29 |
0.51 µg/g body weight/d from pairing-hatching |
TOX-REPRO - reproductive success |
Through hatching |
Dietary |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
Decreased |
Egg size |
NR |
Embryo |
|
28 |
0.51 µg/g body weight/d from pairing-hatching |
TOX-REPRO - physiology |
Through hatching |
Dietary |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
No effect |
Eggshell thickness |
NR |
Embryo |
|
28 |
In ovo, 0.51 µg/g body weight/d parent diet |
TOX-REPRO - physiology |
Through hatching |
In ovo |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
No effect |
Fledging success |
NR |
Fledgling |
|
29 |
In ovo, 0.51 µg/g body weight/d parent diet |
TOX-REPRO - reproductive success |
Through hatching |
In ovo |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
No effect |
Hatching success |
NR |
Embryo |
|
28 |
In ovo, 0.51 µg/g body weight/d parent diet |
TOX-REPRO - reproductive success |
Through hatching |
In ovo |
Toxicity Factor Datasets |
HEXABROMOCYCLODODECANE (HBCDD) |
No effect |
Fertility |
NR |
Adult |
|
29 |
0.51 µg/g body weight/d from pairing-hatching |
TOX-REPRO - reproductive success |
Through hatching |
Dietary |
Toxicity Factor Datasets |
BENZENE |
No effect |
Body weight |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - whole animal |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |
BENZENE |
See citation |
Plasma FT3 |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |
BENZENE |
Decreased |
Plasma FT4 |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |
BENZENE |
Decreased |
Plasma TT4 |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |
BENZENE |
Decreased |
Plasma T4 |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |
BENZENE |
See citation |
Thyroid histology |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - organ/system effects |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |
BENZENE |
No effect |
Hepatic T4-ORD activity |
F |
Adult |
|
17 |
Mixutre: 0.6 ppm benzene, 1 ppm toluene, 2 ppm nitrogen dioxide, 5.6 ppm sulfur dioxide |
TOX-Non-Repro-Sublethal - cellular/biochemical effects |
1.4 h/day, 5d/w, 18 d |
Airborne |
Toxicity Factor Datasets |