Species
Filter by Toxicity Endpoint Type
TOX-EXP IND - accumulation (2271) TOX-EXP IND - biomarkers (33) TOX-MORT - dose-response data (103) TOX-MORT - mortality in the field (42) TOX-MORT - toxicity benchmarks (285) TOX-Non-Repro-Sublethal - behavioral effects (97) TOX-Non-Repro-Sublethal - cellular/biochemical effects (367) TOX-Non-Repro-Sublethal - genetic effects (3) TOX-Non-Repro-Sublethal - indirect effects (11) TOX-Non-Repro-Sublethal - organ/system effects (195) TOX-Non-Repro-Sublethal - whole animal (220) TOX-POP - age distribution effects (1) TOX-POP - size effects (18) TOX-REPRO - behavior (46) TOX-REPRO - development (217) TOX-REPRO - physiology (172) TOX-REPRO - reproductive success (160)
Filter by Exposure Endpoint Type
Age at Fledging, Metamorphosis, Weaning (58) Age at Sexual Maturity (95) Body Fat (total or %) (76) Body length (235) Body Weight - Mean (834) Clutches or Litters per year (92) Clutch or Litter Size (422) Dietary Composition (569) Duration of Incubation or Gestation (98) Fledging or Weaning Rate (127) Food Ingestion Rate (143) Foraging Distance (54) Growth Rate (171) Hatching Success (143) Home Range (344) Inhalation Rate (24) Longevity (72) Metabolic Rate (256) Population Density (481) Surface Area (12) Survival/ Mortality (311) Territory Size (48) Time of Fledging or Metamorphosis (38) Time of Hatching or Parturition (87) Time of Mating/ Laying (204) Time of Migration or Dispersal (66) Time of Molt (25) Time of Nesting (58) Time of Torpor or Hibernation (37) Water Ingestion Rate (32)
Filter by Chemical
AROCLOR 1254 ARSENIC (elemental) BORIC ACID CADMIUM (elemental) CADMIUM CHLORIDE CHLORDANE CHLORPYRIFOS CHROMIUM (elemental) COPPER (elemental) CRUDE OILS DDD (4,4'-) DDE (4,4'-) DDT (4,4'-) DDT (Technical Grade Mixture) DIAZINON DIELDRIN ENDOSULFAN ENDRIN Flameretardants GLYPHOSATE HDBP (halogenated dimethyl bipyrroles) HEPTACHLOR EPOXIDE HEXABROMOCYCLODODECANE (HBCDD) HEXACHLOROBENZENE HEXACHLOROCYCLOHEXANE HEXAHYDRO-1,3,5-TRINITRO-1,3,5-TRIAZINE IRON (elemental) IRON COMPOUNDS LEAD (elemental) LEAD ACETATE LEAD COMPOUNDS MANGANESE COMPOUNDS MERCURY (elemental) MERCURY COMPOUNDS METHYLMERCURY METHYLMERCURY CHLORIDE MIREX NICKEL (elemental) OXYCHLORDANE PARATHION PBDE MIXTURE PBDE TECHNICAL MIXTURE, DE-71 PCB PCB 126 (3,3',4,4',5-PENTACHLOROBIPHENYL) POLYCHLORINATED BIPHENYLS SELENIUM (elemental) SELENIUM COMPOUNDS SELENOMETHIONINE TIN, BUTYL ZINC (elemental)
Filter by Location
Alaksa: 3 sites in eastern AK, California: 3 sites between Santa Cruz and Monterey (32) Algonquin Provincal Park, Ontario [lat., 45^o35'N; long., 78^o30'W] (16) Avian Science and Conservation
Centre of McGill University (67) Avian Science and Conservation Centre of McGill
University (36) Bahía Magdalena (56) Bair Island, WM: West Marin Island, SW: South Wilbur Flood Area (20) Baja California (25) Bear River Migratory Bird Refuge (16) Blackfoot Reservoir (27) Chabahar Beach (40) Clear Lake (18) Colorado Desert (16) Frontenac, Eastern Ontario (42) Guadeloupe, French West Indies (60) Gulf of California (38) Hamilton Harbour, Western Lake Ontario (19) Hong Kong (20) Howick Group of Islands (16) Humboldt River (22) Lahontan Reservoir (26) LCRS: Carson Lake & Lahontan Reservoir; Reference site: Ruby Lake & Humboldt River (34) Mandarte Island (41) McGill University (35) Mingo Basin (20) Minidoka National Wildlife Refuge (27) NJ, PA, DE, MD, VA (22) Okanagan Valley (74) Owens Valley, Big Pine (lat., 37^o11'N) (18) Phoenix South Mountain, Maricopa county (17) Pine Barrens (46) Punta Abreojos (58) S Alberta (20) Samanda? & Dörtyol (36) Samandağ & Dörtyol (37) San Francisco State University (42) San Joaquin Experimental Range (24) San Nicolas Island (31) Sao Paulo (38) SE coast (64) See citation (22) Snake and Pigeon Islands, Eastern Lake Ontario (19) Stege Marsh (28) Texas Tech University (24) The Marine Mammal Center (23) Thousand Palms (33) Three southern CA estuaries (21) Tule Lake National Wildlife Refuge (1230 m) (17) U.S. Army Center for Health
Promotion and Preventive Medicine (20) University of Saskatchewan (21) US Army Center for Health Promotion and Preventive Medicine (30)
Citation:
Author(s)
Fairbrother, A. and J. Fowles
Year
Monday, January 1, 1990 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Location
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
SELENITE, SODIUM, SELENOMETHIONINE
increased @ 3.5 mg/L (selenite) or 2.2 mg/L (selenomethionine)
serum ALT enzyme activity versus controls n high selenite and selenomethionine groups.
Male
Adult
laboratory
Controls = 24
Treated = 8
0, 3.5 mg Se/L (as sodium selenite); 2.2 mg Se/L (selenomethionine)
TOX-Non-Repro-Sublethal - cellular/biochemical effects
12 weeks
drinking water
Toxicity Factor Datasets
SELENOMETHIONINE
increased (12-fold)
selenium concentrations in pectoral muscle
Male
Adult
Laboratory
Controls = 24
Treated = 8
0, 2.2 mg Se/L
TOX-EXP IND - accumulation
12 weeks
Drinking water
Toxicity Factor Datasets
Citation:
Author(s)
Srebocan, Emil and Barnett A. Rattner
Year
Friday, January 1, 1988 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Location
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
LEAD (elemental)
decreased
hemoglobin and hematocrit versus controls
Male
Juvenile
Laboratory
8
0, 1 lead shot (no. 4)
TOX-Non-Repro-Sublethal - organ/system effects
Single exposure
Gavage
Toxicity Factor Datasets
LEAD (elemental)
decreased (60%)
blood ALAD activity versus controls
Male
Juvenile
Laboratory
8
0, 1 lead shot (no. 4)
TOX-Non-Repro-Sublethal - cellular/biochemical effects
Single exposure
Gavage
Toxicity Factor Datasets
LEAD (elemental)
increased
blood protoporphyrin levels versus controls
Male
Juvenile
Laboratory
8
0, 1 lead shot (no. 4)
TOX-Non-Repro-Sublethal - cellular/biochemical effects
Single exposure
Gavage
Toxicity Factor Datasets
Citation:
Author(s)
Chasko, G.G., T.R. Hoehn and P. Howell-Heller
Year
Sunday, January 1, 1984 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
LEAD (elemental)
increased @ 5 shot (33%) and repeated 5 shot (40%)
percent mortality versus controls
Both Male and Female
Not Reported
5-6/group
0, 2, 5, 5 (w/5 repeated doses) Pb shot (no. 6)
TOX-MORT - dose-response data
Single dose, except for repeated dose group
Gavage
Toxicity Factor Datasets
LEAD (elemental)
decreased
bw versus controls
Both Male and Female
Not Reported
5-6/group
0, 2, 5, 5 (w/5 repeated doses) Pb shot (no. 6)
TOX-Non-Repro-Sublethal - whole animal
Single dose, except for repeated dose group
Gavage
Toxicity Factor Datasets
LEAD (elemental)
increased @ all doses
Pb concentrations in wing bone and liver
Both Male and Female
Not Reported
5-6/group
0, 2, 5, 5 (w/5 repeated doses) Pb shot (no. 6)
TOX-EXP IND - accumulation
Single dose, except for repeated dose group
Gavage
Toxicity Factor Datasets
Citation:
Author(s)
Heinz, G.H., G.W. Pendleton, A.J. Krynitsky and L.G. Gold
Year
Monday, January 1, 1990 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
SELENOMETHIONINE
liver: C = 7.4(1-e^-0.382t)
muscle: C = 8.0(1-e^-0.037t)
selenium accumulation equations
Both Male and Female
Adult
3
10 ppm Se
TOX-EXP IND - accumulation
42 days
Diet
Toxicity Factor Datasets
SELENOMETHIONINE
liver: C = 7.4e^-0.037t
muscle: C = 5.6e^-0.023t
liver at peak body burden: C = 22.6e^-0.246t + 2.5 e^-0.008t
muscle at peak body burden: C = 6.4e^-0.029t
Loss phase for blood at peak body burden: C = 12.0e^-0.071t
selenium depuration equations
Both Male and Female
Adult
3
10 ppm, doubled weekly, Se
TOX-EXP IND - accumulation
28 days
Diet
Toxicity Factor Datasets
SELENOMETHIONINE
liver: 18.7 d
muscle: 30.1 d
half life of selenium in tissues
Both Male and Female
Adult
3
10 ppm Se
TOX-EXP IND - accumulation
42 days
Diet
Toxicity Factor Datasets
Citation:
Year
Sunday, January 1, 1978 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
CRUDE OILS
decreased @ 5 uL/egg
embryonic weight (females) and crown rump length (both sexes)
Both Male and Female
Hatchling
65 eggs/group
0, 1, or 5 uL
TOX-REPRO - development
Single exposure
Topical on eggshell
Toxicity Factor Datasets
CRUDE OILS
decreased to 65% @ 1 uL/egg); 9% @ 5 uL/egg
embryo survival to 18 days
Both Male and Female
Embryo
65 eggs/group
0, 1, or 5 uL
TOX-REPRO - development
Single exposure
Topical on eggshell
Toxicity Factor Datasets
Citation:
Author(s)
Hoffman, D.J., C.J. Sanderson, L.J. LeCaptain, E. Cromartie and G.W. Pendleton
Year
Wednesday, January 1, 1992 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
SELENOMETHIONINE
increased @ 15 ppm, 60 ppm (adequate protein, no methionine added)
incidence of histopathological changes in livers versus controls
Not Reported
Juvenile
15/group
0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels
TOX-Non-Repro-Sublethal - organ/system effects
4 weeks
Dietary
Toxicity Factor Datasets
SELENOMETHIONINE
decreased @ 60 ppm (regardless of methionine suppl. or protein levels)
body, liver and spleen weights, and tarsus length versus controls
Not Reported
Juvenile
15/group
0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels
TOX-Non-Repro-Sublethal - whole animal
4 weeks
Dietary
Toxicity Factor Datasets
SELENOMETHIONINE
increased @ 15 (GSH-peroxidase only), 60 ppm Se, adequate protein
plasma GSH-peroxidase and alkaline phosphatase activities versus controls
Not Reported
Juvenile
15/group
0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels
TOX-Non-Repro-Sublethal - cellular/biochemical effects
4 weeks
Diet
Toxicity Factor Datasets
Citation:
Author(s)
Heinz, G.H. and L.G. Gold
Year
Thursday, January 1, 1987 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
SELENOMETHIONINE
no effect
distance run in 2 seconds from a fright stimulus vs controls
Not Reported
Chick
32, 14, 14, 14, 11 in the 0, 1, 2, 4, and 8 ppm groups
0, 1, 2, 4, or 8 ppm Se
TOX-Non-Repro-Sublethal - behavioral effects
4 weeks (parents)
parental diet
Toxicity Factor Datasets
Citation:
Author(s)
Heath, R.G., J.W. Spann and J.F. Kreitzer
Year
Wednesday, January 1, 1969 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
DDE (4,4'-)
decreased
% normal hatchlings versus controls
Not Reported
Embryo
492-518, 232-384, and 128-276 for the 0, 10, and 40 ppm DDE groups
0, 10, or 40 ppm
TOX-REPRO - development
2 years
Diet
Toxicity Factor Datasets
DDE (4,4'-)
decreased
number of 14-day old ducklings per hen versus controls
Both Male and Female
Hatchling
274-327, 69-167, and 26-113 for the 0, 10, and 40 ppm DDE groups
0, 10, or 40 ppm
TOX-REPRO - reproductive success
2 years
Diet
Toxicity Factor Datasets
DDE (4,4'-)
increased
% cracked eggs versus controls
Female
Hatchling
666-696, 620-664, and 317-602 for the 0, 10, and 40 ppm DDE groups
0, 10, or 40 ppm
TOX-REPRO - physiology
2 years
Diet
Toxicity Factor Datasets
DDE (4,4'-)
decreased
eggshell thickness versus controls
Female
Adult
20-28, 21-25, and 10-23 for the 0, 10, and 40 ppm DDE groups
0, 10, or 40 ppm
TOX-REPRO - physiology
2 years
Diet
Toxicity Factor Datasets
Citation:
Author(s)
Hudson, R.H., R.K. Tucker and M.A. Haegele
Year
Saturday, January 1, 1972 - 12:00
Chemical
Endpoint Value
Endpoint Description
Range
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
CHLORPYRIFOS
145 mg/kg
LD50
55.8 - 377 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
CHLORPYRIFOS
29.4 mg/kg
LD50
18.6 - 46.7 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
CHLORPYRIFOS
50.4 mg/kg
LD50
32.5 - 78.1 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
CHLORPYRIFOS
83.3 mg/kg
LD50
44.0 - 158 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ENDOSULFAN
27.8 mg/kg
LD50
22.8 - 33.8 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ENDOSULFAN
6.47 mg/kg
LD50
5.19 - 8.05 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ENDOSULFAN
7.89 mg/kg
LD50
5.77 - 10.8 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ENDOSULFAN
34.4 mg/kg
LD50
26.1 - 45.3 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ALDICARB
1.92 mg/kg
LD50
1.55 - 2.37 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ALDICARB
3.60 mg/kg
LD50
2.90 - 4.49 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ALDICARB
6.73 mg/kg
LD50
5.29 - 8.55 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
ALDICARB
4.44 mg/kg
LD50
3.49 - 5.65 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
PARATHION
1.65 mg/kg
LD50
1.40 - 1.96 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
PARATHION
1.44 mg/kg
LD50
1.13 - 1.83 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
PARATHION
1.65 mg/kg
LD50
1.40 - 1.96 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
PARATHION
2.34 mg/kg
LD50
1.98 - 2.78 (95% CI)
Both Male and Female
Juvenile
5
NR
TOX-MORT - toxicity benchmarks
Single exposure
Gavage
Toxicity Factor Datasets
Citation:
Author(s)
Greenburg, R.R., Risebrough, R.W. and D.W. Anderson
Year
Monday, January 1, 1979 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
AROCLOR 1254, DDE (4,4'-)
decreased with all treatments
numbers of mammillary cores and basal caps on eggshell membranes versus controls
Female
Adult
6-8 eggs/group from 10 hens
0, 40 ppm DDE, 40 ppm Aroclor, 40 ppm DDE + 40 ppm Aroclor
TOX-REPRO - physiology
NR
Diet
Toxicity Factor Datasets
Citation:
Author(s)
Sharma, R.P., D.S. Winn and J.B. Low
Year
Thursday, January 1, 1976 - 12:00
Chemical
Endpoint Value
Endpoint Description
Sex
Life Cycle Stage
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
DIELDRIN
decreased @ 10 ppm (serotonin only) and 30 ppm
Serotonin, norepinephrine, and dopamine levels versus controls
Both Male and Female
Juvenile
3-6 per group
0, 4, 10, and 30 ppm Dieldrin
TOX-Non-Repro-Sublethal - cellular/biochemical effects
Second - generation. Exposed 75 days after hatch.
Diet
Toxicity Factor Datasets
Citation:
Author(s)
Hoffman, D.J., C.J. Sanderson, L.J. LeCaptain, E. Cromartie and G.W. Pendleton
Year
Wednesday, January 1, 1992 - 12:00
Endpoint Value
Endpoint Description
Sample Size
Tox Exposure
Toxicity Endpoint Type
Tox Exposure Duration
Tox Exposure Technique
Type
increased @ 15 , 60 ppm (regardless of methionine suppl. or protein levels)
liver GSH-peroxidase activity versus controls
12/group
0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels
TOX-Non-Repro-Sublethal - organ/system effects
4 weeks
Dietary
Toxicity Factor Datasets
Comment