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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | males: 0.15 (0-3.27; PCBs); 0.31 (0.05-1.95; DDE); 0.03 (0-0.30; dieldrin) females: 0.87 (0-6.82; PCBs); 0.63 (0-4.23; DDE); 0.04 (0-0.37; dieldrin) | geometric mean residues (range) in plasma, ppm, wet wt of adult birds | Both Male and Female | Adult | Rankin Inlet | 26 males, 34 females | geometric mean residues in prey species, ppm, wet wt: non-detect. - 2.11(DDE); non-detect. - 6.88 (PCBs); 0 - 0.51 (dieldrin) | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, POLYCHLORINATED BIPHENYLS | liver: 1.58-59.45, PCBs; 0.99-18.84, DDE; 0.06-0.79, dieldrin breast: 0.35-57.30, PCBs; 0.30-16.95, DDE; 0-0.19, dieldrin | range of residues in liver and breast muscle (ppm, wet wt) of 22-31 day old nestlings found dead | Not Reported | Juvenile | Rankin Inlet | 7 birds | geometric mean residues in prey species, ppm, wet wt: non-detect. - 2.11(DDE); non-detect. - 6.88 (PCBs); 0 - 0.51 (dieldrin) | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | no effect | number of viable eggs or young versus "normal" nest success | Not Reported | Juvenile | Peace, Slave, and Mackenzie Rivers | 15 nests | mean residue concentrations in fat of nesting females (ppm, wet wt): 37.3 (DDT), 284 (DDE), 39.5 (DDD), 3.3 (dieldrin), 4.4 (heptachlor epoxide) | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | 0.9-7.2 (DDT); 10.4-41.8 (DDE); 0.9-3.4 (DDD); 0.3-2.0 (dieldrin); 0.2-1.2 (heptachlor epoxide) | range of concentrations in eggs (ppm, wet wt) | Female | Adult | Peace, Slave, and Mackenzie Rivers | 7 eggs | mean (+/- SE) concentrations in fat of nesting females, ppm, wet wt: 37.3 +/- 12.2 (DDT), 284 +/- 62 (DDE), 39.5 +/- 11.2 (DDD), 3.3 +/- 1.3 (dieldrin), 4.4 +/- 2.6 (heptachlor epoxide) | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE | 37.3 (DDT), 284 (DDE), 39.5 (DDD), 3.3 (dieldrin), 4.4 (heptachlor epoxide) | mean residue concentrations in fat (ppm, wet wt) | Female | Adult | Peace, Slave, and Mackenzie Rivers | 9 birds | mean (+/- SE) concentrations in 11 prey samples, ppm, wet wt: 0.13 +/- 0.18 (DDT), 0.66 +/- 0.67 (DDE), 0.11 +/- 0.16 (DDD), 0.01 +/- 0.02 (dieldrin), 0.05 +/- 0.04 (heptachlor epoxide) | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, POLYCHLORINATED BIPHENYLS | 15.8% | mean eggshell thinning compared to "pre-pesticide" reference eggs | Female | Adult | Rankin Inlet | 78 eggs | geometric mean concentration in 52 eggs, ppm, wet wt: 7.59 (DDE); 8.74 (PCBs); 0.41 (dieldrin); 0.36 (heptachlor epoxide) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-), DIELDRIN, HEPTACHLOR EPOXIDE, POLYCHLORINATED BIPHENYLS | log DDE in eggs = 0.9723 + 0.8506(log DDE in plasma); r = 0.66 | log-log relationship between DDE in plasma of female birds and DDE in eggs | Female | Adult | Rankin Inlet | 10 females | range of geometric mean concentrations in prey animals, ppm, wet wt: ND-4.22(DDE); ND-4.21 (PCBs); ND-0.19 (dieldrin); ND-1.73 (heptachlor epoxide) | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.89 (1.27-2.43) -6.96 (3.28-13.37) ppm, wet wt | annual mean (range) concentrations in eggs | Female | Adult | Amchitka Island | 3-6 eggs/year | whole body residues in prey species, ppm, wet wt: 0.006-1.884 | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | 7.5% decrease | eggshell thickness compared to "pre-pesticide" reference eggs | Female | Adult | Amchitka Island | 3-6 eggs/year | annual mean concentrations in eggs (range), ppm, wet wt: 1.89 (1.27-2.43) to 6.96 (3.28-13.37) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 21.7% decrease (tundra population); 16.8% decrease (taiga population); 7.5% decrease (Aleutian population) | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | Colville River (tundra); Yukon River (taiga); Amchitka Island (Aleutian) | 23 eggs (tundra pop.); 14 eggs (taiga pop.); 11 eggs (Aleutian pop.) | mean concentration in eggs, ppm, lipid basis: 889 (tundra); 673 (taiga); 167 (Aleutian) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 48.0 (DDE), 3.35 (DDD), 1.02 (DDT), 1.45 (dieldrin) | mean concentrations of pesticides in eggs (ppm, dry weight) | Female | Adult | Yukon River | 2 eggs | range of mean concentrations in prey items, ppm dry wt: 0.32-6.02 (DDE), 0.07-0.17 (DDD), 0.09-0.19 (DDT), 0.00-0.11 (dieldrin) | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
DDD (4,4'-), DDE (4,4'-), DDT (4,4'-), DIELDRIN | 622.0 (DDE), 25.4 (DDD), 25.3 (DDT), 6.20 (dieldrin) | mean concentrations of pesticides in fat (ppm, dry weight) | Both Male and Female | Adult | Yukon River | 4 birds | range of mean concentrations in prey items, ppm dry wt: 0.32-6.02 (DDE), 0.07-0.17 (DDD), 0.09-0.19 (DDT), 0.00-0.11 (dieldrin) | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 6.4-33 ppm, dry wt | range of concentrations in whole addled eggs | Female | Adult | 5 eggs from 3 clutches | 0.01-8.78 ppm, wet wt, in composite prey samples | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | 14.2% | percent eggshell thinning compared to pre-1947 reference eggs | Female | Adult | 26 breeding attempts | 0.01-8.78 ppm, wet wt, in composite prey samples | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
HEPTACHLOR EPOXIDE | negative correlation | correlation of heptachlor epoxide concentration in eggs and eggshell thickness | Female | Adult | 38 eggs | 0.10-1.10 ppm, wet wt, in eggs | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | 21:0.09 | ratio of average concentration of DDE in eggs to average concentration of DDE in prey items | Female | Adult | 12 prey species, pooled samples of 7-10 individuals | range of mean concentrations in prey species: 0.04-6.0 ppm, wet wt | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | eggshell thickness index = 1.799 - 0.243(log DDE) | linear regression of eggshell thickness index vs. log DDE concentration in eggs | Female | Adult | 295 eggs | range of mean concentrations in eggs: 0.58-15.19 ppm, wet wt | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | brood size = 0.848 - 0.635(log DDE) - 0.271(log Hg) | linear regression of brood size vs mercury and DDE concentrations in eggs | Female | Adult | 60 eggs | range of geometric mean concentrations in eggs: 0.21-1.27 ppm, dry wt | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | productivity = 1.412 - 0.724(log DDE) | linear regression of productivity (mean number of young raised per pair) vs. log DDE concentration in eggs | Both Male and Female | Adult | 14 pairs | range of mean concentrations in eggs: 0.58-15.19 ppm, wet wt | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-), HEPTACHLOR EPOXIDE | 15 ppm DDE, 0.7 ppm heptachlor epoxide | concentrations in eggs associated with population recovery | Both Male and Female | Both Adults and Juveniles | 550 eggs from 469 clutches | range of mean concentrations in eggs, ppm, wet wt: 0.58-15.19 (DDE); 0.01 - 0.77 (heptachlor epoxide) | TOX-POP - size effects | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-), POLYCHLORINATED BIPHENYLS | 11.4% | percent eggshell thinning compared to pre-DDT reference eggs | Female | Adult | Kola Peninsula | 8 nests | geom. mean concentrations in eggs, ppm, wet wt: 3.5 (DDE), 7.3 (PCBs), wet wt, in eggs (geometric means) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
MERCURY (elemental) | 2.80 - 10.60 ppm, dry wt (females) 3.70 - 8.95 ppm, dry wt (males) | range of concentrations measured in primary and rectrix feathers | Both Male and Female | Adult | Southern Sweden | 3 sample periods; 1-9 birds/sample period | < 0.1 to between 0.1 and 0.2 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | 6.90-29.50 ppm, dry wt (females) 12.10 ppm, dry wt (males) | concentrations measured in primary and rectrix feathers | Both Male and Female | Adult | Northern Sweden | 20 females, 1 male | < 0.1 to >0.4 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | 2.79 (3.10) ppm, dry wt | mean (SD) concentration measured in feathers | Not Reported | Juvenile | Southern Sweden | 3 nests | < 0.1 to between 0.1 and 0.2 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
MERCURY (elemental) | 8.31(2.59) ppm, dry wt | mean (SD) concentration measured in feathers | Not Reported | Juvenile | Northern Sweden | 3 nests | < 0.1 to >0.4 ppm, wet wt, in pectoral muscles of avian prey species | TOX-EXP IND - accumulation | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 16% | percent eggshell thinning compared to pre-1947 reference eggs | Female | Adult | South Australia | 13 eggs | 3.98 ppm, wet wt, in eggs | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | eggshell thickness index = 1.888 - 0.281(log DDE) | linear regression of eggshell thickness index and DDE content of eggs | Female | Adult | Tasmania, Victoria, South Australia | 137 eggs | 1.8-12.4 ppm, wet wt, in eggs (range of geometric means) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
DDE (4,4'-) | productivity = 1.79 - 0.04(DDE) | linear regression of productivity (number of young fledged per site) and DDE concentrations in eggs | Both Male and Female | Adult | Tasmania | 9 eggs | range of geometric means, ppm, wet wt: 2.0-6.1 (eggs); 0.06 - 1.78 (typical prey items) | TOX-REPRO - reproductive success | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | review | data correlating eggshell thinning and DDE concentrations in eggs | Female | Adult | Not Reported | NR | TOX-REPRO - physiology | NR | NR | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no relation | linear regression of eggshell thickness and DDE concentration in eggs | Female | Adult | Victoria | 35 eggs | range of concentrations, ppm, wet wt: 2.30 to 82.00 (eggs); negligible to 0.74 (representative prey species) | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | no effect | eggshell thickness compared to pre-1947 reference eggs | Female | Adult | 2 eggs, 1 nest | 0.69-1.40 ppm, wet wt, in eggs | TOX-REPRO - physiology | NR | environmental contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DIBENZ[A]ANTHRACENE (1,2,5,6-) | 5 | description | Both Male and Female | Adult | location | sample size | exposure | TOX-MORT - toxicity benchmarks | duration | route | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
FONOFOS, TERBUFOS | no effect | reproductive parameters (reproductive success, clutch size, number of unhatched eggs, number of young fledged/nest) of nests located on edges of sprayed fields | Both Male and Female | Both Adults and Juveniles | southwestern Ontario | 60 treatment, 32 control nests | 6 fields treated with fonofos; 5 fields treated with terbufos (application rates were according to recommended guidelines, Ontario Ministry of Agriculture and Food) | TOX-REPRO - reproductive success | NR | field application | Toxicity Factor Datasets |
FONOFOS, TERBUFOS | no effect | survival of banded individuals, pre- versus post-application, up to 50 days post-application | Both Male and Female | Adult | southwestern Ontario | 88 males, 44 females (treatment); 69 males, 27 females (control) | 6 fields treated with fonofos; 5 fields treated with terbufos (application rates were according to recommended guidelines, Ontario Ministry of Agriculture and Food) | TOX-MORT - mortality in the field | NR | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PENTACHLOROBENZENE | no effect | mean body mass and appearance of eyes, gums, teeth and fur, compared to controls | Both Male and Female | Adult | 3/dose | 0, 65, 130, 260, 520 mg/animal | TOX-Non-Repro-Sublethal - whole animal | single | oral via capsule | Toxicity Factor Datasets |
PENTACHLOROBENZENE | no effect | serum chemistry and hematological profile, compared to control | Both Male and Female | Adult | 3/dose | 0, 65, 130, 260, 520 mg/animal | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | oral via capsule | Toxicity Factor Datasets |
PENTACHLOROBENZENE | see citation | figures of feces and serum concentrations over time at the tested doses | Both Male and Female | Adult | 3/dose | 0, 65, 130, 260, 520 mg/animal | TOX-EXP IND - accumulation | single | oral via capsule | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHOXYCHLOR | no appreciable mortality | embryo and larvae (10 d post-hatch) mortality | Not Reported | Embryo, Juvenile | 30-34 eggs/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-MORT - dose-response data | 45 d | waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | decrease @ 0.1, 0.3, 1, 3, 10 mg/L | mean day of hatch, compared to controls | Not Reported | Embryo, Juvenile | 30-34 eggs/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-REPRO - development | 35 d | waterborne | Toxicity Factor Datasets |
METHOXYCHLOR | decrease @ 0.3, 1, 3, 10 mg/l | responsiveness to startle and distance travelled post-startle in larvae | Not Reported | Juvenile | 30-34 eggs exposed/dose; 14-27 larvae tested/dose | 0, 0.03, 0.1, 0.3, 1.0, 3.2, 10.0 mg/L (DMSO carrier) | TOX-REPRO - behavior | 45 d | waterborne | Toxicity Factor Datasets |