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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | food consumption versus controls | Both Male and Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-Non-Repro-Sublethal - behavioral effects | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | decreased in 3rd generation | eggshell thickness versus controls | Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - physiology | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | increased in 2nd generation | proportion of eggs laid outside nestbox | Female | Adult | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - behavior | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | no effect | hatchability and duckling survival versus controls | Not Reported | Juvenile | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - reproductive success | NR | diet | Toxicity Factor Datasets |
METHYLMERCURY DICYANDIAMIDE | decreased in 3rd generation | proportion of ducklings responding to approach and avoidance stimuli | Not Reported | Juvenile | 14 pairs/group | 0, 0.5 ppm Hg in diet | TOX-REPRO - development | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
LEAD (elemental) | no effect | body weight compared to controls | Both Male and Female | Adult | 20 females, 10 males/group | 0, 1, 2 lead shot (206 mg avg wt) | TOX-Non-Repro-Sublethal - whole animal | Single dose (one shot); repeated dose (two shot) | Gavage | Toxicity Factor Datasets |
LEAD (elemental) | no effect | egg production versus controls | Female | Adult | 20 females/group | 0, 1, 2 lead shot (206 mg avg wt) | TOX-REPRO - reproductive success | Single dose (one shot); repeated dose (two shot) | Gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENITE, SODIUM, SELENOMETHIONINE | no effect | tarsus length, 10th primary length, heart weight versus controls | Not Reported | Juvenile | 40 birds/group | 0, 10 ppm Se as selenomethionine or sodium selenite | TOX-Non-Repro-Sublethal - whole animal | 6 weeks | Diet | Toxicity Factor Datasets |
SELENITE, SODIUM | 18(4.8) ppm, wet wt @ 40 ppm; 6.9(2.07) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenite that died | Not Reported | Juvenile | 40 birds/group | 0, 10, 20, 40, or 80 ppm Se as sodium selenite | TOX-EXP IND - accumulation | 6 weeks | Diet | Toxicity Factor Datasets |
SELENOMETHIONINE | 60(14.2) ppm, wet wt @ 40 ppm; 51(5.2) ppm, wet wt @ 80 ppm | mean liver concentrations (SE) in ducklings fed selenomethionine that died | Not Reported | Juvenile | 40 birds/group | 0, 10, 20, 40, or 80 ppm Se as selenomethionine | TOX-EXP IND - accumulation | 6 weeks | Diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decreased @ 1, 5 uL/egg | bill length of both sexes | Both Male and Female | Hatchling | 65 eggs/group | 0, 1, or 5 uL | TOX-REPRO - development | Single exposure | Topical on eggshell | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
SELENOMETHIONINE | no effect | % survival versus controls | Not Reported | Juvenile | 15/group | 0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels | TOX-MORT - dose-response data | 4 weeks | Dietary | Toxicity Factor Datasets |
SELENOMETHIONINE | 11.6 (@15 ppm diet), 48.6 (@ 60 ppm diet) ppm, wet wt | geometric mean Se concentration in liver (adequate protein in diet) | Not Reported | Juvenile | 15/group | 0, 15, or 60 ppm Se; with and without added methionine, and varying protein levels | TOX-EXP IND - accumulation | 4 weeks | Dietary | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | decrease @ 5, 15 ul/egg | red blood cell and liver ALAD activity, hemoglobin concentration, plasma uric acid, and plasma ALT and AST activities compared to controls | Both Male and Female | Hatchling | 100 eggs/dose | 0, 2, 5, 15 ul waste crankcase oil/egg | TOX-REPRO - physiology | single | application to egg surface | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increased with light, moderate and heavy oiling | thermal conductance of feathers and body heat loss versus controls | Both Male and Female | Adult | 3 birds/treatment | 0, light, moderate, and heavy exposure | TOX-Non-Repro-Sublethal - whole animal | single exposure, 1-4 hrs | in bathing water | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PENTACHLOROPHENOL | decrease @ 961 ug/g | total body weight, compared to control; reported as the LOAEL for the study | Not Reported | Juvenile | 6/dose | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-REPRO - development | 11 d | diet | Toxicity Factor Datasets |
PENTACHLOROPHENOL | no effect @ 423.2 ug/g | total body weight, compared to control; reported as the NOAEL for the study | Not Reported | Juvenile | 6/dose | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-REPRO - development | 11 d | diet | Toxicity Factor Datasets |
PENTACHLOROPHENOL | 22.2 +/- 5.5 ug/g lipid, 30.7 +/- 10.3 ug/g liver, 11.0 +/- 0 ug/g muscle, 4.0 +/- 1.4 ug/g brain at 961 ug/g diet | mean +/- SD tissue concentrations at the reported LOAEL (development) | Not Reported | Juvenile | 4-6 | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-EXP IND - accumulation | 11 d | diet | Toxicity Factor Datasets |
PENTACHLOROPHENOL | 12.2 +/- 2.3 ug/g lipid, 20.7 +/- 3.7 ug/g liver, 3.3 +/- 1.6 ug/g muscle, 2.6 +/- 1.5 ug/g brain at 423.2 ug/g diet | mean +/- SD tissue concentrations at the reported NOAEL (development) | Not Reported | Juvenile | 6-8 | 25.0, 54.2, 105.0, 233.2, 423.2, 961.0 ug/g diet | TOX-EXP IND - accumulation | 11 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DIELDRIN | no effect | total body weight, compared to control | Not Reported | Juvenile | 4-6/dose | <0.2, 2.6, 26.2, 49.3 ug/g diet | TOX-REPRO - development | 8 d | diet | Toxicity Factor Datasets |
DIELDRIN | 9.7 ug/g lipid, 3.3 ug/g skin, 1.3 ug/g brain, 0.8 ug/g liver, 0.7 ug/g muscle at 2.6 ug/g food | mean of day 5, 7, 8 (approx. steady state) tissue concentrations | Not Reported | Juvenile | 6 | <0.2, 2.6, 26.2, 49.3 ug/g diet | TOX-EXP IND - accumulation | 8 d | diet | Toxicity Factor Datasets |
DIELDRIN | 42.5 ug/g lipid, 14.6 ug/g skin, 1.6 ug/g brain, 2.5 ug/g liver, 1.2 ug/g muscle at 26.2 ug/g food | mean of day 5, 7, 8 (approx. steady state) tissue concentrations | Not Reported | Juvenile | 6 | <0.2, 2.6, 26.2, 49.3 ug/g diet | TOX-EXP IND - accumulation | 8 d | diet | Toxicity Factor Datasets |
DIELDRIN | 80.7 ug/g lipid, 30.1 ug/g skin, 1.6 ug/g brain, 4.1 ug/g liver, 1.8 ug/g muscle at 49.3 ug/g food | mean of day 5, 7, 8 (approx. steady state) tissue concentrations | Not Reported | Juvenile | 6 | <0.2, 2.6, 26.2, 49.3 ug/g diet | TOX-EXP IND - accumulation | 8 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLMERCURY DICYANDIAMIDE | 0.51-0.54 ppm blood, 2.07-2.41 ppm kidney, 2.35-2.26 ppm liver, 0.74-0.97 ppm breast muscle, 0.47-0.51 ppm brain, 0.88 ppm eggs @ 0.5 ppm in diet | range of mean Hg (ppm wet-weight) concentrations in wild-strain males and females | Both Male and Female | Adult | 6-9 (9 breeding pairs/dose) | control and 0.5 mg Hg/kg diet (Hg as methylmercury dicyandiamide) | TOX-EXP IND - accumulation | 22 Dec. to 27 July, 1976; approx. 7 mo | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 10.6 +/- 2.2 ppm nasal gland, 16.1 +/- 5.1 ppm liver, 5.8 +/- 1.1 ppm kidney, 1.9 +/- 0.1 ppm brain @ 100 ppm diet | mean (+/- SE) DDE levels (ppm wet weight) | Both Male and Female | Juvenile | 4 | control or 100 ppm DDE | TOX-EXP IND - accumulation | 7 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | no effect | nasal gland secretion volume | Both Male and Female | Juvenile | 5-11 | control, 10, 50 ppm DDE | TOX-Non-Repro-Sublethal - organ/system effects | 7 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | no effect | nasal gland and kidney Na-K-ATPase activity, following exposure to 100% seawater | Both Male and Female | Juvenile | 4-5 | control or 100 ppm DDE | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 7 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | no effect | body weight or plasma electrolyte levels | Both Male and Female | Juvenile | 4 | control, 10-100 ppm DDE | TOX-Non-Repro-Sublethal - whole animal | 7 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 1.23 +/- 0.12 ug/g wet weight | mean +/- SE p,p'-DDE concentration in shell gland mucosa | Female | Adult | Not Reported | control, 40 mg/kg dry weight diet | TOX-EXP IND - accumulation | 45 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 28% decrease @ 40 mg/kg | eggshell index (shell weight/shell length x breadth), compared to control | Female | Adult | 9-20/group | control, 40 mg/kg dry weight diet | TOX-REPRO - physiology | 45 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | no effect | plasma calcium concentration | Female | Adult | Not Reported | control, 40 mg/kg dry weight diet | TOX-Non-Repro-Sublethal - organ/system effects | 45 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 25% decrease @ 40 mg/kg | calcium content of secreted fluid in the shell gland, compared to control | Female | Adult | 5/dose | control, 40 mg/kg dry weight diet | TOX-REPRO - physiology | 45 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DDE (4,4'-) | 18% decrease @ 40 mg/kg | eggshell index (shell weight/length x breadth), compared to control | Female | Adult | 18 | control, 40 mg/kg dry weight | TOX-REPRO - physiology | 45 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 38 ug/g wet weight egg (yolk + white), 1.20 ug/g wet weight egg shell gland mucosa @ 40 mg/kg | mean DDE concentrations | Female | Adult | 7-9 | control, 40 mg/kg dry weight | TOX-EXP IND - accumulation | 45 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 32% decrease @ 40 mg/kg | Ca2+-Mg2+ ATPase activity in eggshell gland mucosa homogenates, compared to controls | Female | Adult | Not Reported | control, 40 mg/kg dry weight | TOX-REPRO - physiology | 45 d | diet | Toxicity Factor Datasets |
DDE (4,4'-) | 44% increase @ 40 mg/kg | calcium content (umol/g dry weight) of eggshell gland mucosa, compared to controls | Female | Adult | Not Reported | control, 40 mg/kg dry weight | TOX-REPRO - physiology | 45 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
STRYCHNINE | increase | strychnine poisoning via grain bait diagnosed as cause of death in free-flying mallards | Both Male and Female | Adult | Saskatoon, Saskatchewan | 4 | 19.7 - 85.1 mg strychnine/kg ingesta | TOX-MORT - mortality in the field | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | no effect | body weight; body and skin temperature at 16C; mean heat production and thermal conductance at 16C | Not Reported | Adult | 5/dose | control, 5 ml/kg bird/d Statfjord A crude oil | TOX-Non-Repro-Sublethal - whole animal | 6 d | gavage | Toxicity Factor Datasets |
CRUDE OILS | increase | body temperature at an ambient temperature of -17C, compared to control | Not Reported | Adult | 5/dose | control, 5 ml/kg bird/d Statfjord A crude oil | TOX-Non-Repro-Sublethal - whole animal | 6 d | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CRUDE OILS | increase @ 1% and 3% | hepatic microsomal naphthalene metabolism (nmol/min/mg protein), compared to control, in adult females and in neonatal ducklings hatched from eggs laid by females (1% Prudhoe Bay dose level was not significantly different for neonates). | Female | Adult | 6 adults/dose; 5-20 neonates/dose | control, 1%, 3% (ml oil/100 g dry wt food); South Louisiana and Prudhoe Bay crude oil | TOX-Non-Repro-Sublethal - cellular/biochemical effects | NR | diet | Toxicity Factor Datasets |