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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FENTHION | 16.9% @ 5mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
DICROTOPHOS | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
DICROTOPHOS | 70.1% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
MALATHION | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
MALATHION | 90.6% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
ACEPHATE | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
ACEPHATE | 109.7% @ 5mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
PARATHION | 100% @ 1 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | logarithmically spaced does up to 1 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
PARATHION | 9% @ 1 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 6/dose | logarithmically spaced does up to 1 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
FENTHION | 67% @ 2.2 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | logarithmically spaced does up to 1 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 63% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | 0, 2.4 mg/kg bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | oral gavage | Toxicity Factor Datasets |
FENTHION | 61% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | 0, 5.5 mg/kg bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | oral gavage | Toxicity Factor Datasets |
DICROTOPHOS, FENTHION | 68-78% | maximal brain acetylcholinesterase activity inhibition compared to control (after 3 days treatmentt) | Not Reported | Juvenile | 4/group | 16 mg dicrotophos/kg diet OR 17 mg fenthion/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 13 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | 357 ppm | 11 day dietary LC50 | Not Reported | Juvenile | 10/group | 0, 56, 100, 178, 316, 562 ppm diet | TOX-MORT - toxicity benchmarks | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | 236 ppm | 11 day dietary LC10 | Not Reported | Juvenile | 10/group | 0, 56, 100, 178, 316, 562 ppm diet | TOX-MORT - toxicity benchmarks | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | 0, 56, 100,178, 316, 562 ppm diet | TOX-Non-Repro-Sublethal - behavioral effects | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | 0, 56, 100, 178, 316, 562 ppm diet | TOX-Non-Repro-Sublethal - whole animal | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | 644 ppm (declining to 141 ppm over 11 d) | 5 day dietary LC50, when 5 day residue half life was simulated | Not Reported | Juvenile | 10/group | 0, 112, 200, 356, 632, 1124 ppm diet (initial concentrations; declined over 11 day treatment period) | TOX-MORT - toxicity benchmarks | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | 0, 112, 200, 356, 632, 1124 ppm diet (initial concentrations; declined over 11 day treatment period) | TOX-Non-Repro-Sublethal - behavioral effects | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | 0, 112, 200, 356, 632, 1124 ppm diet (initial concentrations; declined over 11 day treatment period) | TOX-Non-Repro-Sublethal - whole animal | 11 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ASULAM | 10% @ 4000 mg/kg | percent mortality after 21 days | Both Male and Female | Juvenile | 10/dose | 0, 1600, 2600, 4000 mg/kg bw | TOX-MORT - dose-response data | single | oral | Toxicity Factor Datasets |
ASULAM | decreased @ all doses | food consumption compared with controls | Both Male and Female | Juvenile | 10/dose | 0, 33,750, 55,000, 75,000, 100,000 mg/kg diet | TOX-Non-Repro-Sublethal - behavioral effects | 5 d | diet | Toxicity Factor Datasets |
ASULAM | decreased @ all doses | body weight gain by day 8 compared with controls | Both Male and Female | Juvenile | 10/dose | 0, 33,750, 55,000, 75,000, 100,000 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 5 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | decreased @ all doses | food consumption compared with controls | Both Male and Female | Juvenile | 10/dose | 0, 330, 500, 750, 1100, 1650, 2500 mg/kg diet | TOX-Non-Repro-Sublethal - behavioral effects | 5 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | decreased @ all doses | body weight gain by 8 days compared with controls | Both Male and Female | Juvenile | 10/dose | 0, 330, 500, 750, 1100, 1650, 2500 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 5 d | diet | Toxicity Factor Datasets |
DDT (4,4'-) | 1550 ppm | 5 day dietary LC50 | Both Male and Female | Juvenile | 10/dose | 0, 330, 500, 750, 1100, 1650, 2500 mg/kg diet | TOX-MORT - toxicity benchmarks | 5 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CARBOFURAN | increased @ 132 and 264 g/ha | occurrence of acute poisoning symptoms compared with controls | Not Reported | Juvenile | 29-38/group | 0, 132, 264 g carbofuran/ha | TOX-Non-Repro-Sublethal - behavioral effects | single | pesticide application; subjects walked 50, 150, or 300 m through application areas | Toxicity Factor Datasets |
CARBOFURAN | increased @ 264 g/ha (150, 300 m exposure distance) | latency of approach to stimulus compared with controls | Not Reported | Juvenile | 8/group | 0, 132, 264 g carbofuran/ha | TOX-Non-Repro-Sublethal - behavioral effects | single | pesticide application; subjects walked 50, 150, or 300 m through application areas | Toxicity Factor Datasets |
CARBOFURAN | decreased @ 132 g/ha (150, 300 m exposure distances), 264 g/ha (all exposure distances) | brain cholinesterase activities compared with controls | Not Reported | Juvenile | 8/group | 0, 132, 264 g carbofuran/ha | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | pesticide application; subjects walked 50, 150, or 300 m through application areas | Toxicity Factor Datasets |
CARBOFURAN | no effect | growth rate to four weeks of age compared with controls | Not Reported | Juvenile | 8/group | 0, 132, 264 g carbofuran/ha | TOX-Non-Repro-Sublethal - whole animal | single | pesticide application; subjects walked 50, 150, or 300 m through application areas | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHYLPARATHION | no effect | number of eggs per incubated nest and percent fertility of eggs compared with controls | Both Male and Female | Adult | 12 pairs/group | 400 ppm diet, beginning at egg laying, early incubation, or late incubation periods | TOX-REPRO - reproductive success | 8 d | diet | Toxicity Factor Datasets |
METHYLPARATHION | decreased if treatment initiated during egg laying | proportion of hens laying and number of eggs laid per hen compared to controls | Female | Adult | 12 pairs /group | 400 ppm diet, beginning at egg laying, early incubation, or late incubation periods | TOX-REPRO - physiology | 8 d | diet | Toxicity Factor Datasets |
METHYLPARATHION | 2/12 when treatment initiated during early incub.; 2/11 when treatment initiated during late incub. | incidence of adult mortality during incubation compared with controls | Female | Adult | 12 pairs/group | 400 ppm diet, beginning at egg laying, early incubation, or late incubation periods | TOX-MORT - dose-response data | 8 d | diet | Toxicity Factor Datasets |
METHYLPARATHION | increased when treatment initiated during early or late incub. | incidence of nest abandonment compared with controls | Female | Adult | 12 pairs/group | 400 ppm diet, beginning at egg laying, early incubation, or late incubation periods | TOX-Non-Repro-Sublethal - behavioral effects | 8 d | diet | Toxicity Factor Datasets |
METHYLPARATHION | no effect | number of hatchlings per nest, percent hatchability, hatchling survival and body weight to 5 days compared with controls | Not Reported | Hatchling | 12 pairs/group | 400 ppm diet, beginning at egg laying, early incubation, or late incubation periods | TOX-REPRO - reproductive success | 8 d | diet | Toxicity Factor Datasets |
METHYLPARATHION | decreased when treatment initiated during laying, early or late incub. | food consumption compared with controls | Female | Adult | 12 pairs/group | 400 ppm diet, beginning at egg laying, early incubation, or late incubation periods | TOX-Non-Repro-Sublethal - behavioral effects | 8 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PARATHION | decreased @ 0.75, 7.5 (aqueous) or 0.8 (oil) lb/acre | embryo weight by day 18 of incubation compared with controls | Not Reported | Embryo | 30/group | 0, 0.75, 7.5 lb/acre simulated, aqueous; 0, 0.08, 0.8 lb/acre simulated, oil | TOX-REPRO - development | single | application to eggshell surface | Toxicity Factor Datasets |
MALATHION | increased @ 125 lb/acre | cumulative mortality by day 18 compared with controls | Not Reported | Embryo | 30/group | 12.5, 125 lb/acre simulated, aqueous; 0, 1.4, 14.0 lb/acre simulated, oil | TOX-MORT - dose-response data | single | application to eggshell surface | Toxicity Factor Datasets |
MALATHION | 118 (day 3), 101 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | 12.5, 125 lb/acre simulated, aqueous | TOX-MORT - toxicity benchmarks | single | application to eggshell surface | Toxicity Factor Datasets |
PARATHION | 41(day 3), 39 (day 8) lb/acre | LC50, exposed on day 3 or 8 of incubation | Not Reported | Embryo | 30/group | 0.75, 7.5 lb/acre simulated, aqueous | TOX-MORT - toxicity benchmarks | single | application to eggshell surface | Toxicity Factor Datasets |