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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
FENTHION | 96% | range of plasma cholinesterase inhibition (relative to control) in birds that died | Male | Adult | 14 | 1.1-6.1 ug/g sparrow | TOX-EXP IND - biomarkers | 1-3 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | 0.24 ug/g at study area, 0.087 ug/g at reference area | mean lead concentration in blood (wet wt) | Both Male and Female | Nestling | Coeur D'Alene River | 30 (study area) 22 (reference) | 3.0-1640 ug/g (wet wt) in prey species | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | 0.46 ug/g at study area 0.25 ug/g at reference area | mean lead concentration in blood (wet wt) | Both Male and Female | Adult | Coeur D'Alene River | 3 (study area) 6 (reference) | 3.0-1640 ug/g (wet wt) in prey species | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | decreased | red blood cell delta aminolevulinic acid dehydratase activity (relative to control) | Both Male and Female | Both Adults and Juveniles | Coeur D'Alene River | 33 | 3.0-1640 ug/g (wet wt) in prey species | TOX-EXP IND - biomarkers | NR | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | decreased | hematocrit | Both Male and Female | Juvenile | Coeur D'Alene River | 30 | 3.0-1640 ug/g (wet wt) in prey species | TOX-Non-Repro-Sublethal - cellular/biochemical effects | NR | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | decreased | hemoglobin (relative to control) | Both Male and Female | Both Adults and Juveniles | Coeur D'Alene River | 33 | 3.0-1640 ug/g (wet wt) in prey species | TOX-Non-Repro-Sublethal - cellular/biochemical effects | NR | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | 0.23 ug/g (wet wt) | mean lead concentration in liver | Both Male and Female | Juvenile | Coeur D'Alene River | 30 | 3.0-1640 ug/g (wet wt) in prey species | TOX-EXP IND - accumulation | NR | diet | Toxicity Factor Datasets |
LEAD COMPOUNDS | no effect | number of young produced | Both Male and Female | Adult | Coeur D'Alene River | 20 nests | 3.0-1640 ug/g (wet wt) in prey species | TOX-REPRO - reproductive success | NR | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
DDT (Technical Grade Mixture) | 6.42 ppm | mean DDT concentration in eggs 0-0.8 mi from sprayed area | Both Male and Female | Embryo | La Grande-Enterprise (OR), Potlatch (ID) | 21 eggs | 0.75 lb/ac application | TOX-EXP IND - accumulation | 1 yr | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | 10.4% decrease | change in mean eggshell thickness (relative to control) 0-0.8 miles from sprayed area | Female | Adult | La Grande-Enterprise (OR), Potlatch (ID) | 21 eggs | 0.75 lb/ac application | TOX-REPRO - physiology | 1 yr | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | no effect | mean productivity (young produced) | Both Male and Female | Adult | La Grande-Enterprise (OR), Potlatch (ID) | 21 eggs | 0.75 lb/ac application | TOX-REPRO - reproductive success | 1 yr | diet | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | 0.78 ppm | mean DDT concentration in plasma of birds sampled 0-1.5 mi from sprayed area | Both Male and Female | Adult | La Grande-Enterprise (OR), Potlatch (ID) | 23 birds | 0.75 lb/ac application | TOX-EXP IND - accumulation | 1 yr | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
HEPTACHLOR | increase at 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
ENDOSULFAN | increase at 0.1 and 0.5 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
CHLORDECONE (KEPONE) | no effect | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 0.5 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
DDT (Technical Grade Mixture) | increase at 1.0 lbs/acre | Not Reported | Tadpole | ponds, southern San Joaquin Valley | 10 animals/dose | 0.1, 1.0 lbs/acre | TOX-MORT - mortality in the field | single application | waterborne | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
GLYPHOSATE | no effect | population density (decreases) | Both Male and Female | Both Adults and Juveniles | University of British Columbia Research Forest, Maple Ridge, British Columbia | Not Reported | 2.2 kg/ha | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TERBUFOS | increase @ 1.69 and 2.48 mg/kg | Both Male and Female | Not Reported | 70 animals/dose | 0, 0.92, 1.69 and 2.48 g active ingredient/kg | TOX-MORT - dose-response data | single | gavage | Toxicity Factor Datasets | |
TERBUFOS | decrease at 1.69 and 2.48 mg/kg | brain cholinesterase activity | Both Male and Female | Not Reported | 70 animals/dose | 0, 0.92, 1.69 and 2.48 g active ingredient/kg | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | gavage | Toxicity Factor Datasets |
TERBUFOS | increase @ 1.69 and 2.48 mg/kg | incidence of tremors and rapid breathing | Both Male and Female | Not Reported | 70 animals/dose | 0, 0.92, 1.69 and 2.48 g active ingredient/kg | TOX-Non-Repro-Sublethal - behavioral effects | single | gavage | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|
ALDICARB | no effect | food intake | Female | 8 animals/dose | 0, 10, 10,000 ug/l | TOX-Non-Repro-Sublethal - behavioral effects | 44 d | drinking water | Toxicity Factor Datasets |
ALDICARB | no effect | growth rate estimated by changes in body weight | Female | 8 animals/dose | 0, 10, 10,000 ug/l | TOX-Non-Repro-Sublethal - organ/system effects | 44 d | drinking water | Toxicity Factor Datasets |
ALDICARB | no effect | daily activity measured as time spend in burrow or moving in/out of burrow | Female | 8 animals/dose | 0, 10, 10,000 ug/l | TOX-Non-Repro-Sublethal - behavioral effects | 44 d | drinking water | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
METHIOCARB | effect @ 0.03-0.5% | suppression of feeding on treated corn | Both Male and Female | Not Reported | 10 - 12 animals/dose | 0, 0.03, 0.125, 0.5% active ingredient by weight of corn seed | TOX-Non-Repro-Sublethal - behavioral effects | 1 - 6 d | diet | Toxicity Factor Datasets |
THIRAM | effect at 0.03-0.5% | suppression of feeding on treated corn | Both Male and Female | Not Reported | 10 - 12 animals/dose | 0, 0.31, 1.25% active ingredient by weight of corn seed | TOX-Non-Repro-Sublethal - behavioral effects | 1 - 6 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
GLYPHOSATE | no effect | recruitment measured as number of new animals that entered the population through reproduction or immigration in treated and control areas | Both Male and Female | Both Adults and Juveniles | University of British Columbia Research Forest, Maple Ridge, British Columbia | Not Reported | 0, 3.0 kg active ingredient /ha | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |
GLYPHOSATE | no effect | body weight | Both Male and Female | Both Adults and Juveniles | University of British Columbia Research Forest, Maple Ridge, British Columbia | 67 - 138 animals | 0, 3.0 kg active ingredient /ha | TOX-Non-Repro-Sublethal - whole animal | single | field application | Toxicity Factor Datasets |
GLYPHOSATE | no effect | growth rate, estimated by changes in body weight | Both Male and Female | Juvenile | University of British Columbia Research Forest, Maple Ridge, British Columbia | 23 - 55 | 0, 3.0 kg active ingredient /ha | TOX-REPRO - development | single | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
RADIONUCLIDES | 160 +/- 162SE mrem/d; range = 7-982 mrem/d | whole animal dose estimated with implanted dosimeters | Not Reported | Not Reported | test reactor area, Idaho National Engineering Lab | 70 animals | Air: 10 - 2000 mroetgen/d | TOX-EXP IND - accumulation | NR | site contamination | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
AMINOCARB | no effect | mean activity level estimated by frequency of crossing sand transects | Not Reported | Not Reported | southwestern Quebec [lat., 46^oN; long., 74^o10'W] | Not Reported | 0, 175 g active ingredient/ha | TOX-Non-Repro-Sublethal - behavioral effects | single | field application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
LEAD COMPOUNDS | Bone; 52.10 +/- 33.81SD, Kidney; 8.46 +/- 3.03SE, Liver; 3.29 +/- 1.77SD, Brain; 0.84 +/- 0.25SE, Feces; 153.6+/- 103.5SD ppm (dry weight) | Mean concentrations in deer mice from roadside site (ppm, dry weight). Feces collected from nest box after 1 yr accumulation. Roadside tissue concentrations significantly different from control site. | Both Male and Female | Adult | Interstate 25, Denver (elev. 1884-2018 m) | 9 - 10 animals | mean surface soil; 73.0 +/- 19.9SD ppm, dry weight | TOX-EXP IND - accumulation | NR | multiple | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Cu concentration versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-EXP IND - accumulation | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | increased @ 10, 50 ug/g diet | kidney Zn concentration versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-EXP IND - accumulation | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | BW versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - whole animal | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | brain, liver, kidney, testes weights versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - whole animal | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | liver glycogen concentration versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - organ/system effects | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | % packed cell volume versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - organ/system effects | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | plasma glucose, NEFA, urea, or uric acid versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | thyroid hormone concentrations versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 42 days | Diet | Toxicity Factor Datasets |
CADMIUM CHLORIDE | no effect | adrenal wt, corticosterone concentrations versus controls | Male | Adult | 8 | 0, 10, or 50 ug Cd/g | TOX-Non-Repro-Sublethal - organ/system effects | 42 days | Diet | Toxicity Factor Datasets |