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Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
TRICHLOROPHENOXYACETIC ACID (2,4,5-) | 106 lbs AI/acre (slope = 3.7) for exposure of 3d embryo; 116 lbs AI/acre (slope = 3.8) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | 3-6 doses (lbs/acre) @ 100 gal emulsifiable concn./acre | TOX-MORT - toxicity benchmarks | single | in ovo, immersion | Toxicity Factor Datasets |
LINDANE | 8.5 lbs AI/acre (slope = 1.34) for exposure of 3d embryo; 7.3 lbs AI/acre (slope = 2.72) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | 3-6 doses (lbs/acre) @ 11 gal oil base carrier/acre | TOX-MORT - toxicity benchmarks | single | in ovo, external application | Toxicity Factor Datasets |
PARAQUAT | 0.1 lbs AI/acre (slope = 2.10) for exposure of 3d embryo; 0.2 lbs AI/acre (slope = 3.29) for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | 3-6 doses (lbs/acre) @ 11 gal oil base carrier/acre | TOX-MORT - toxicity benchmarks | single | in ovo, external application | Toxicity Factor Datasets |
TOXAPHENE (POLYCHLORINATED CAMPHENES) | 66 lbs AI/acre for exposure of 3d embryo; 66 lbs AI/acre for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | 3-6 doses (lbs/acre) @ 11 gal oil base carrier/acre | TOX-MORT - toxicity benchmarks | single | in ovo, external application | Toxicity Factor Datasets |
TRICHLOROPHENOXYACETIC ACID (2,4,5-) | 44 lbs AI/acre for exposure of 3d embryo; 44 lbs AI/acre for exposure of 8d embryo | LC50 | Not Reported | Embryo | 30/dose | 3-6 doses (lbs/acre) @ 11 gal oil base carrier/acre | TOX-MORT - toxicity benchmarks | single | in ovo, external application | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 101.8 (coeff. of variation = 21.6%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | 0, 40, 55, 76, 105, 145, 200 ppm diet | TOX-MORT - toxicity benchmarks | 5 days | diet | Toxicity Factor Datasets |
DIELDRIN | 155.8 (coeff. of variation = 16.0%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | 0, 75, 93, 116, 145, 180, 225 ppm diet | TOX-MORT - toxicity benchmarks | 5 days | diet | Toxicity Factor Datasets |
DICROTOPHOS | decreased @ 55 and 145 ppm | consumption of treated diet compared with controls | Not Reported | Juvenile | 8-10/dose | 0, 40, 55, 76, 105, 145, 200 ppm diet | TOX-Non-Repro-Sublethal - behavioral effects | 5 days | diet | Toxicity Factor Datasets |
DICROTOPHOS | 506.7 (coeff. of variation = 40.3%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | 0, 120, 158, 209, 276, 360 ppm diet | TOX-MORT - toxicity benchmarks | 5 days | diet | Toxicity Factor Datasets |
DIELDRIN | 200.7 (coeff. of variation 22.3%) | 5 day dietary LC50 | Not Reported | Juvenile | 8-10/dose | 0, 100, 132, 173, 228, 300 ppm diet | TOX-MORT - toxicity benchmarks | 5 days | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | decreased | body weight compared to controls | Both Male and Female | Adult | 24 pairs/dose | 0, 80 (+/- 10%) ppm | TOX-Non-Repro-Sublethal - whole animal | 19 weeks | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased | brain acetylcholinesterase activity compared to controls | Both Male and Female | Adult | 24 pairs/dose | 0, 80 (+/- 10%) ppm | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 19 weeks | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased | number of eggs produced, egg weight, eggshell thickness compared to controls | Both Male and Female | Adult | 24 pairs/dose | 0, 80 (+/- 10%) ppm | TOX-REPRO - physiology | 19 weeks | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | no effect | fertility and hatchability of eggs, and duckling survival to 14 days | Not Reported | Juvenile | 24 pairs/dose | 0, 80 (+/- 10%) ppm | TOX-REPRO - reproductive success | 19 weeks | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
PARATHION | 100% @ 5mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
PARATHION | 0.8% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
FENTHION | 100% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
FENTHION | 16.9% @ 5mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
DICROTOPHOS | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
DICROTOPHOS | 70.1% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
MALATHION | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
MALATHION | 90.6% @ 5 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
ACEPHATE | 0% @ 5 mg/L | percent mortality | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
ACEPHATE | 109.7% @ 5mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 4-5/dose | 0, 5 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
PARATHION | 100% @ 1 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | logarithmically spaced does up to 1 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
PARATHION | 9% @ 1 mg/L | brain acetylcholinesterase activity compared with controls | Not Reported | Juvenile | 6/dose | logarithmically spaced does up to 1 mg/L in water of dietary tadpoles (96 hours) | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | diet | Toxicity Factor Datasets |
FENTHION | 67% @ 2.2 mg/L | percent mortality | Not Reported | Juvenile | 6/dose | logarithmically spaced does up to 1 mg/L in water of dietary tadpoles (96 hours) | TOX-MORT - dose-response data | single | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
DICROTOPHOS | 63% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | 0, 2.4 mg/kg bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | oral gavage | Toxicity Factor Datasets |
FENTHION | 61% | maximal brain acetylcholinesterase activity inhibition compared to control (4 hrs post-dose) | Not Reported | Juvenile | 4/group | 0, 5.5 mg/kg bw | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | oral gavage | Toxicity Factor Datasets |
DICROTOPHOS, FENTHION | 68-78% | maximal brain acetylcholinesterase activity inhibition compared to control (after 3 days treatmentt) | Not Reported | Juvenile | 4/group | 16 mg dicrotophos/kg diet OR 17 mg fenthion/kg diet | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 13 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
CHLORPYRIFOS | 357 ppm | 11 day dietary LC50 | Not Reported | Juvenile | 10/group | 0, 56, 100, 178, 316, 562 ppm diet | TOX-MORT - toxicity benchmarks | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | 236 ppm | 11 day dietary LC10 | Not Reported | Juvenile | 10/group | 0, 56, 100, 178, 316, 562 ppm diet | TOX-MORT - toxicity benchmarks | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | 0, 56, 100,178, 316, 562 ppm diet | TOX-Non-Repro-Sublethal - behavioral effects | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | 0, 56, 100, 178, 316, 562 ppm diet | TOX-Non-Repro-Sublethal - whole animal | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | 644 ppm (declining to 141 ppm over 11 d) | 5 day dietary LC50, when 5 day residue half life was simulated | Not Reported | Juvenile | 10/group | 0, 112, 200, 356, 632, 1124 ppm diet (initial concentrations; declined over 11 day treatment period) | TOX-MORT - toxicity benchmarks | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | 0, 112, 200, 356, 632, 1124 ppm diet (initial concentrations; declined over 11 day treatment period) | TOX-Non-Repro-Sublethal - behavioral effects | 11 d | diet | Toxicity Factor Datasets |
CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | 0, 112, 200, 356, 632, 1124 ppm diet (initial concentrations; declined over 11 day treatment period) | TOX-Non-Repro-Sublethal - whole animal | 11 d | diet | Toxicity Factor Datasets |
Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
---|---|---|---|---|---|---|---|---|---|---|
ASULAM | 10% @ 4000 mg/kg | percent mortality after 21 days | Both Male and Female | Juvenile | 10/dose | 0, 1600, 2600, 4000 mg/kg bw | TOX-MORT - dose-response data | single | oral | Toxicity Factor Datasets |
ASULAM | decreased @ all doses | food consumption compared with controls | Both Male and Female | Juvenile | 10/dose | 0, 33,750, 55,000, 75,000, 100,000 mg/kg diet | TOX-Non-Repro-Sublethal - behavioral effects | 5 d | diet | Toxicity Factor Datasets |
ASULAM | decreased @ all doses | body weight gain by day 8 compared with controls | Both Male and Female | Juvenile | 10/dose | 0, 33,750, 55,000, 75,000, 100,000 mg/kg diet | TOX-Non-Repro-Sublethal - whole animal | 5 d | diet | Toxicity Factor Datasets |