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| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GLYPHOSATE | decrease | number of hardwood trees in study area | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 1 study area | 2.2 kg/ha | TOX-Non-Repro-Sublethal - indirect effects | NR | field application | Toxicity Factor Datasets |
| GLYPHOSATE | no effect | proportion of trapped animals in breeding condition | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 151 | 2.2 kg/ha | TOX-REPRO - physiology | NR | field application | Toxicity Factor Datasets |
| GLYPHOSATE | increase | survival over summer and winter | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 545 | 2.2 kg/ha | TOX-MORT - mortality in the field | NR | field application | Toxicity Factor Datasets |
| GLYPHOSATE | no effect | juvenile growth rate (summer and fall) | Both Male and Female | Both Adults and Juveniles | Maple Ridge, BC | 283 | 2.2 kg/ha | TOX-REPRO - physiology | NR | field application | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|
| GLYPHOSATE | 0.29 | relative density (vs. control) in sprayed area | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-POP - size effects | field application | Toxicity Factor Datasets |
| GLYPHOSATE | decrease | percent vegetation cover (vs control) in study area | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-Non-Repro-Sublethal - indirect effects | field application | Toxicity Factor Datasets |
| GLYPHOSATE | no effect | adult sex ratios | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-POP - size effects | field application | Toxicity Factor Datasets |
| GLYPHOSATE | no effect | age structure as indicated by number of juveniles trapped | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-POP - age distribution effects | field application | Toxicity Factor Datasets |
| GLYPHOSATE | increase | mean number of foeti in trapped females | Both Male and Female | Both Adults and Juveniles | Vancouver Island | 285 | 1.1-1.2 kg/ha application | TOX-REPRO - reproductive success | field application | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|
| CHLOROCHOLINE CHLORIDE | increase @ 1, 20, 80 mg/kg bw/d | liver weight to bw ratio | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | diet | Toxicity Factor Datasets |
| CHLOROCHOLINE CHLORIDE | increase @ 1-80 mg/kg | thymus weight to bw ratios | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | Diet | Toxicity Factor Datasets |
| CHLOROCHOLINE CHLORIDE | increase @ 80 mg/kg bw/d | white blood cell counts | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
| CHLOROCHOLINE CHLORIDE | increase @ 80 mg/kg bw/d | plaque forming cells/g spleen | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
| CHLOROCHOLINE CHLORIDE | decrease @ 80 mg/kg bw/d | reciprocal of hemolysin titers (against sheep rbc) | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
| GLYPHOSATE | increase @ 20, 80 mg/kg bw/d | liver weight to body weight ratio | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | Diet | Toxicity Factor Datasets |
| GLYPHOSATE | increased @ 1-80 mg/kg | thymus weight to bw ratio | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - organ/system effects | 28 d | Diet | Toxicity Factor Datasets |
| GLYPHOSATE | increase@ 80 mg/kg bw/d | white blood cell count | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
| GLYPHOSATE | increase @ 80 mg/kg bw/d | plaque forming cell count/g spleen | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
| GLYPHOSATE | no effect | reciprocal of hemolysin titer (against sheep rbc) | Female | Adult | 12/dose | 0, 1, 10, 20, 40, 80 mg/kg bw/d | TOX-Non-Repro-Sublethal - cellular/biochemical effects | 28 d | Diet | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DICHLOROPHENOXY-ACETIC ACID (2,4-) | no effect | changes in population density; treated versus control site | Not Reported | Both Adults and Juveniles | Gunnison County and Saquache County, (elev., 8500 - 9300 ft.) | 6 study areas/dose | 0, 2-3 lbs/acre | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |
| DICHLOROPHENOXY-ACETIC ACID (2,4-) | no effect | mean litter size, based upon number of viable embryos or placental scars | Female | Adult | Gunnison County and Saquache County, (elev., 8500 - 9300 ft.) | 66-77 animals | 0, 2-3 lbs/acre | TOX-REPRO - reproductive success | single | field application | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|
| DIPHACINONE | increase at 0.0025% | Both Male and Female | Not Reported | 10 animals/dose | 0.00125, 0.0025, 0.005, 0.01, 0.02% | TOX-MORT - dose-response data | 2 d | diet | Toxicity Factor Datasets |
| CHLOROPHACINONE | increase at 0.00125% | Both Male and Female | Not Reported | 10 animals/dose | 0.00125, 0.0025, 0.005, 0.01, 0.02% | TOX-MORT - dose-response data | 2 d | diet | Toxicity Factor Datasets |
| DIPHACINONE | increase @ 0.00125- 0.02% | Both Male and Female | Not Reported | 10 animals/dose | 0.00125, 0.0025, 0.005, 0.01, 0.02% | TOX-MORT - dose-response data | 4 d | diet | Toxicity Factor Datasets |
| CHLOROPHACINONE | increase @ 0.00125-0.02% | Both Male and Female | Not Reported | 10 animals/dose | 0.00125, 0.0025, 0.005, 0.01, 0.02% | TOX-MORT - dose-response data | 4 d | diet | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ARSENIC COMPOUNDS, CADMIUM COMPOUNDS, COPPER COMPOUNDS, LEAD COMPOUNDS, ZINC COMPOUNDS | Arsenic, <0.02; Cadmium, 0.08; Copper, 3.4; Lead, <0.003; Zinc, 29.5 ug/g | mean carcass concentration (ug/g wet wt.); mean deer mice body weight = 36.0 +/- 8.3SD, n=8 | Not Reported | Not Reported | Milltown Reservoir, Missoula | 8 animals | Mining waste; Mean soil concentrations (n=8): Arsenic, 52.5 +/- 6.2; Cadmium, 7.8 +/- 0.7; Copper, 532.2 +/- 69.4; Lead, 65.7 +/- 6.4; Zinc, 1,908.9 +/- 392.9SE ug/g | TOX-EXP IND - accumulation | NR | site contamination | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| AZINPHOS-METHYL (GUTHION) | decrease @ 3.61 kg/ha | population density in enclosures with mowed alfalfa | Both Male and Female | Both Adults and Juveniles | Hyslop Crop Science Field Laboratory, Corvallis | 0-30 animals/enclosure; 4 enclosures/dose | 0, 0.88, 3.61 kg/ha | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DIELDRIN | decrease at 5 mg/kg | homing orientation test, measured as time in maze pointing to capture site | Both Male and Female | Both Adults and Juveniles | NR | 15 animals/dose | 0, 5 mg/kg | TOX-Non-Repro-Sublethal - behavioral effects | single | intraperitoneal | Toxicity Factor Datasets |
| DIELDRIN | decrease at 5 mg/kg | homing, measured as number recaptured at pre-exposure site | Both Male and Female | Both Adults and Juveniles | NR | 15 animals/dose | 0, 5 mg/kg | TOX-Non-Repro-Sublethal - behavioral effects | single | intraperitoneal | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GLYPHOSATE | no effect | population density (decreases) | Both Male and Female | Both Adults and Juveniles | University of British Columbia Research Forest, Maple Ridge, British Columbia | Not Reported | 2.2 kg/ha | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|
| TERBUFOS | increase @ 1.69 and 2.48 mg/kg | Both Male and Female | Not Reported | 70 animals/dose | 0, 0.92, 1.69 and 2.48 g active ingredient/kg | TOX-MORT - dose-response data | single | gavage | Toxicity Factor Datasets | |
| TERBUFOS | decrease at 1.69 and 2.48 mg/kg | brain cholinesterase activity | Both Male and Female | Not Reported | 70 animals/dose | 0, 0.92, 1.69 and 2.48 g active ingredient/kg | TOX-Non-Repro-Sublethal - cellular/biochemical effects | single | gavage | Toxicity Factor Datasets |
| TERBUFOS | increase @ 1.69 and 2.48 mg/kg | incidence of tremors and rapid breathing | Both Male and Female | Not Reported | 70 animals/dose | 0, 0.92, 1.69 and 2.48 g active ingredient/kg | TOX-Non-Repro-Sublethal - behavioral effects | single | gavage | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|
| ALDICARB | no effect | food intake | Female | 8 animals/dose | 0, 10, 10,000 ug/l | TOX-Non-Repro-Sublethal - behavioral effects | 44 d | drinking water | Toxicity Factor Datasets |
| ALDICARB | no effect | growth rate estimated by changes in body weight | Female | 8 animals/dose | 0, 10, 10,000 ug/l | TOX-Non-Repro-Sublethal - organ/system effects | 44 d | drinking water | Toxicity Factor Datasets |
| ALDICARB | no effect | daily activity measured as time spend in burrow or moving in/out of burrow | Female | 8 animals/dose | 0, 10, 10,000 ug/l | TOX-Non-Repro-Sublethal - behavioral effects | 44 d | drinking water | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|
| METHIOCARB | effect @ 0.03-0.5% | suppression of feeding on treated corn | Both Male and Female | Not Reported | 10 - 12 animals/dose | 0, 0.03, 0.125, 0.5% active ingredient by weight of corn seed | TOX-Non-Repro-Sublethal - behavioral effects | 1 - 6 d | diet | Toxicity Factor Datasets |
| THIRAM | effect at 0.03-0.5% | suppression of feeding on treated corn | Both Male and Female | Not Reported | 10 - 12 animals/dose | 0, 0.31, 1.25% active ingredient by weight of corn seed | TOX-Non-Repro-Sublethal - behavioral effects | 1 - 6 d | diet | Toxicity Factor Datasets |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Location | Sample Size | Tox Exposure | Toxicity Endpoint Type | Tox Exposure Duration | Tox Exposure Technique | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GLYPHOSATE | no effect | recruitment measured as number of new animals that entered the population through reproduction or immigration in treated and control areas | Both Male and Female | Both Adults and Juveniles | University of British Columbia Research Forest, Maple Ridge, British Columbia | Not Reported | 0, 3.0 kg active ingredient /ha | TOX-POP - size effects | single | field application | Toxicity Factor Datasets |
| GLYPHOSATE | no effect | body weight | Both Male and Female | Both Adults and Juveniles | University of British Columbia Research Forest, Maple Ridge, British Columbia | 67 - 138 animals | 0, 3.0 kg active ingredient /ha | TOX-Non-Repro-Sublethal - whole animal | single | field application | Toxicity Factor Datasets |