Toxicological foundations of ecological risk assessment: biomarker development and interpretration based on laboratory and wildlife species

Author(s)

Dickerson, Richard L., Michael J. Hooper, Nicholas W. Gard, George P. Cobb and Ronald J. Kendall

Year

Sat, 01/01/1994 - 12:00

Article Title

Toxicological foundations of ecological risk assessment: biomarker development and interpretration based on laboratory and wildlife species

Volume

102

Issue

Supp.

Pages

65-69

Start Page Number

Final Page

Review

Datapoints

Displaying 1 - 5 of 5 datapoints.

Species: Deer Mouse (Peromyscus maniculatus)
Chemical	Toxicity Endpoint Type	Endpoint Description	Endpoint Value	Sample Size	Life Cycle Stage	Study Duration	Type
METHYLCHLORANTHRENE (3-)	TOX-Non-Repro-Sublethal - organ/system effects	ED50 for immunosuppression, measured as suppression of plaque forming cell response	0.14 mg/kg/d	Not Reported	Juvenile	11 d	Toxicity Factor Datasets
METHYLCHLORANTHRENE (3-)	TOX-Non-Repro-Sublethal - cellular/biochemical effects	ED50 for ethoxyresorufin-O-dealkylase (EROD) activity	1.24 mg/kg/d	Not Reported	Juvenile	11 d	Toxicity Factor Datasets
DIBENZ[A]ANTHRACENE (1,2,5,6-)	TOX-Non-Repro-Sublethal - organ/system effects	ED50 for immunosuppression, measured as suppression of plaque forming cell response	0.048 mg/kg/d	Not Reported	Juvenile	11 d	Toxicity Factor Datasets
DIBENZ[A]ANTHRACENE (1,2,5,6-)	TOX-Non-Repro-Sublethal - cellular/biochemical effects	ED50 for ethoxyresorufin-O-dealkylase (EROD) activity	0.85 mg/kg/d	Not Reported	Juvenile	11 d	Toxicity Factor Datasets
DIMETHYLBENZ[A]ANTHRACENE (7,12-)	TOX-Non-Repro-Sublethal - organ/system effects	ED50 for immunosuppression, measured as suppression of plaque forming cell response	0.026 mg/kg/d	Not Reported	Juvenile	11 d	Toxicity Factor Datasets