NICKEL SULFATE

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Mallard duck (Anas platyrhynchos)

Citation:

Effects of dietary nickel on mallards

Author(s)
Eastin, William C., Jr. and Thomas J. O'Shea
Pages
883-892
Year
Volume
7
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
NICKEL SULFATE increased @ 200, 800 ppm food consumption compared to controls Both Male and Female Adult 6 pairs/group Toxicity Factor Datasets Laboratory
NICKEL SULFATE no effects body wt, liver wt:brain wt, kidney wt:brain wt, duodenal wt compared to controls Both Male and Female Adult 6 pairs/group Toxicity Factor Datasets Laboratory
NICKEL SULFATE no effects plasma biochemistry compared to controls Male Adult 6 pairs/group Toxicity Factor Datasets Laboratory
NICKEL SULFATE no effects reproductive success (number of eggs laid, hatchability, duckling survival) compared to controls Both Male and Female Adult 6 pairs/group Toxicity Factor Datasets Laboratory
NICKEL SULFATE increased @ 12.5, 50, 200, 800 ppm diet kidney, blood, liver, and feather concentrations of Ni compared to controls Both Male and Female Adult 6 pairs/group Toxicity Factor Datasets Laboratory
NICKEL SULFATE 1.94 (kidney), 0.52 (liver), 0.139 (blood), 68.06 (feathers) ppm, wet wt mean tissue concentrations @ 800 ppm Ni in diet Both Male and Female Adult 6 pairs/group Toxicity Factor Datasets Laboratory
Citation:

Effects of dietary nickel on survival and growth of mallard ducklings

Author(s)
Cain, Brian W. and Ellen A. Pafford
Pages
737-745
Year
Volume
10
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
NICKEL SULFATE increased @ 800, 1200 ppm incidence of clinical signs and mortality Both Male and Female Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
NICKEL SULFATE decreased @ 1200 ppm body wt by 28 d of age Both Male and Female Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
NICKEL SULFATE no effect bill length Both Male and Female Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
NICKEL SULFATE decreased @ 1200 pmm (30 d of age) weight:length of humerus Male Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
NICKEL SULFATE decreased @ all doses (by 60 d of age) weight:length of humerus Female Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
NICKEL SULFATE no effect organ wt:body wt ratios Both Male and Female Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
NICKEL SULFATE 1.0-22.7 (liver), 2.7-74.4 (kidney) ppm, wet wt Ni concentrations (ranges) in liver and kidney in ducklings that died @ 1200 ppm Both Male and Female Juvenile 36 birds/dose Toxicity Factor Datasets 14 d Laboratory
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OEHHA California Office of Environmental Health Hazard Assessment