METHYLPARATHION
Bullfrog (Lithobates catesbeianus formerly Rana catesbeiana)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Countries | Lab |
|---|---|---|---|---|---|---|---|---|---|
| METHYLPARATHION | 79.5 | in loco heart rate | Not Reported | Tadpole | 36 | NR | Toxicity Factor Datasets | BRAZIL | Laboratory |
Mallard duck (Anas platyrhynchos)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| METHYLPARATHION | decreased if treatment initiated during egg laying | proportion of hens laying and number of eggs laid per hen compared to controls | Female | Adult | 12 pairs /group | Toxicity Factor Datasets | 7 mo | Laboratory | |
| METHYLPARATHION | 2/12 when treatment initiated during early incub.; 2/11 when treatment initiated during late incub. | incidence of adult mortality during incubation compared with controls | Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory | |
| METHYLPARATHION | increased when treatment initiated during early or late incub. | incidence of nest abandonment compared with controls | Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory | |
| METHYLPARATHION | no effect | number of hatchlings per nest, percent hatchability, hatchling survival and body weight to 5 days compared with controls | Not Reported | Hatchling | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory | |
| METHYLPARATHION | decreased when treatment initiated during laying, early or late incub. | food consumption compared with controls | Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory | |
| METHYLPARATHION | no effect | number of eggs per incubated nest and percent fertility of eggs compared with controls | Both Male and Female | Adult | 12 pairs/group | Toxicity Factor Datasets | 7 mo | Laboratory |
American Kestrel (Falco sparverius)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| METHYLPARATHION | increased at 2, 3 mg/kg bw | abnormal posture, ataxia, paresis | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | increase at 3 mg/kg bw | mortality rate 2 hr post-dose | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | decrease at 2, 3 mg/kg bw | cloacal temperature | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | decrease at 2, 3 mg/kg bw | plasma cholinesterase activity 2 hr post-dose | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | decrease at 1, 2, 3 mg/kg bw | brain acetylcholinesterase activity 10 hr post-dose | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | increased at 2, 3 mg/kg bw | plasma glucose concentrations | Both Male and Female | Adult | 5/dose | Toxicity Factor Datasets | Laboratory |
Western Toad (Anaxyrus boreas formerly Bufo boreas)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| METHYLPARATHION | decrease @ 25 and 50 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | Toxicity Factor Datasets | Laboratory |
Merriam's Kangaroo Rat (Dipodomys merriami)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab |
|---|---|---|---|---|---|---|---|---|
| METHYLPARATHION | no effect | discrimination between seeds and beads | Both Male and Female | Adult | 22 animals | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | 18-19 % decrease | brain cholinesterase activity, compared to control | Both Male and Female | Adult | 2 animals | Toxicity Factor Datasets | Laboratory | |
| METHYLPARATHION | 97.1 mg/kg (95% CI, 42.6-178.6 mg/kg) | LD50 | Both Male and Female | Adult | 3-4 animals/group | Toxicity Factor Datasets | Laboratory |
Mourning Dove (Zenaida macroura)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type |
|---|---|---|---|---|---|---|---|
| AZINPHOS-METHYL (GUTHION), DIMETHOATE, ENDOSULFAN, METHYLPARATHION, PARATHION, PERMETHRIN, THIRAM, ZIRAM | decreased in conventional orchards | daily survival rates | Not Reported | Nestling | 29 conventional nests | York Springs, Adams Co. | Toxicity Factor Datasets |
| AZINPHOS-METHYL (GUTHION), DIMETHOATE, ENDOSULFAN, METHYLPARATHION, PARATHION, PERMETHRIN, THIRAM, ZIRAM | decreased in conventional orchards | hatching success | Not Reported | Nestling | 29 conventional nests | York Springs, Adams Co. | Toxicity Factor Datasets |
| AZINPHOS-METHYL (GUTHION), DIMETHOATE, ENDOSULFAN, METHYLPARATHION, PARATHION, PERMETHRIN, THIRAM, ZIRAM | no effect | numbers of eggs laid or number of fledglings produced | Not Reported | Both Adults and Juveniles | 29 conventional nests | York Springs, Adams Co. | Toxicity Factor Datasets |
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