METHYLMERCURY CHLORIDE

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Mallard duck (Anas platyrhynchos)

Citation:

Methylmercury chloride and selenomethionine interactions on health and reproduction in mallards

Author(s)
Heinz, Gary H., and David J. Hoffman
Pages
139-145
Year
Issue
2
Volume
17
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
METHYLMERCURY CHLORIDE, SELENOMETHIONINE 7.6(0.26) ppm, egg, 6.0(0.31) ppm, fem. liver, 9.6(0.95) ppm, male liver @ 10 ppm Se; 9.3(0.85) ppm, egg, 9.2(1.61) ppm, female liver, 114(25.3) ppm, male liver @ 10 ppm Se + 10 ppm Hg mean(SE) wet wt concentration of Se in egg and liver of treated birds Both Male and Female Adult 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE 16(0.8) ppm, egg, 22(1.5) ppm, fem. liver, 71(8.9) ppm, male liver @ 10 ppm Hg; 17(0.6) ppm, egg, 21(4.3) ppm, female liver, 65(4.1) ppm, male liver @ 10 ppm Se + 10 ppm Hg mean(SE) wet wt concentration of Hg in egg and liver of treated birds Both Male and Female Adult 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE no effect body weight versus controls Both Male and Female Adult 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE increased @ 10 ppm Hg incidence of leg weakness versus controls Male Adult 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE decreased @ 10 ppm Hg, 10 ppm Hg + 10 ppm Se hatchability versus controls Both Male and Female Both Adults and Juveniles 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE no effect egg laying interval, egg weight, egg shell thickness, fertility, duckling survival, hatchling body weights versus controls Both Male and Female Both Adults and Juveniles 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE reduced @ 10 ppm Se, 10 ppm Hg + 10 ppm Se weight of 7 day old ducklings versus controls Both Male and Female Both Adults and Juveniles 12/group Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE increased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se incidence of deformities in embryos that died (1 wk or older) versus controls Both Male and Female Both Adults and Juveniles 12/group Toxicity Factor Datasets 18 mo Laboratory
Citation:

Effects of industrial effluents, heavy metals, and organic solvents on mallard embryo development

Author(s)
Hoffman, David J. and William C. Eastin, Jr.
Pages
35-40
Year
Volume
9
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
METHYLMERCURY CHLORIDE decreased @ all doses embryo length or weight by incubation day 18 versus controls Not Reported Embryo 30 eggs/group Toxicity Factor Datasets 3 or 8 days of incubation (time of treatment) Laboratory
METHYLMERCURY CHLORIDE decreased @ 5,000 ppm, incub. day 3 exposure embryo survival through day 18 of incubation and % of survivors that were normal versus controls Not Reported Embryo 30 eggs/group Toxicity Factor Datasets 3 or 8 days of incubation (time of treatment) Laboratory
Citation:

Effects of mercury and selenium on glutathione metabolism and oxidative stress in mallards

Author(s)
Hoffman, David J., and Gary H. Heinz
Pages
161-166
Year
Issue
2
Volume
17
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
METHYLMERCURY CHLORIDE, SELENOMETHIONINE reduced @ 10 ppm Se, 10 ppm Se + 10 ppm Hg hematocrit and hemoglobin values versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE increased @ 10 ppm Hg + 10 ppm Se plasma glucose concentrations versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE decreased @ 10 ppm Se, 10 ppm Hg, 10 ppm Hg + 10 ppm Se plasma phosphorus concentrations versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE decreased @ 10 ppm Hg glutathione peroxidase activity (plasma and liver) and glucose-6-phosphate dehydrogenase (liver and brain) versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE increased @ 10 ppm Se hepatic GSSG reductase activity versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE increased @ 10 ppm Hg oxidized glutathione (GSSG) level versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE reduced @ 10 ppm Hg, 10 ppm Hg + 10 ppm Se protein-bound sulfhydryl in liver versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE increased @ 10 ppm Hg, 10 ppm Se, 10 ppm Hg + 10 ppm Se thiobarbituric acid-reactive substances in brain versus controls Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE 3.4(0.22) ppm @ 10 ppm Se; 5.2(0.44) ppm @ 10 ppm Hg + 10 ppm Se mean (SE) wet wt Se concentrations in brain Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
METHYLMERCURY CHLORIDE, SELENOMETHIONINE 17.9(1.06) ppm @ 10 ppm Hg; 14.1(0.74) ppm @ 10 ppm Hg + 10 ppm Se mean (SE) wet wt Hg concentrations in brain Male Adult 12/treatment Toxicity Factor Datasets 18 mo Laboratory
Citation:

Mercury accumulation in mallards fed methylmercury with or without added DDE

Author(s)
Heinz, Gary H.
Pages
372-376
Year
Volume
42
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
DDE (4,4'-), METHYLMERCURY CHLORIDE 1.4 +/- 0.18 (@ 1 ppm, no DDE), 8.7 +/- 0.87 (@ 5 ppm, no DDE) ppm Hg, wet wt mean Hg concentration in third egg laid in clutch (mean +/- SE) Female Adult 10/group Toxicity Factor Datasets Laboratory
DDE (4,4'-), METHYLMERCURY CHLORIDE 1.0 +/- 0.06 (@ 1 ppm Hg, no DDE), 5.3 +/- 0.56 (@ 5 ppm Hg, no DDE) ppm Hg, wet wt Hg concentration in breast muscle (mean +/- SE) Female Adult 10/group Toxicity Factor Datasets Laboratory
Citation:

Teratogenic effects of external egg applications of methyl mercury in the mallard, Anas platyrynchos

Author(s)
Hoffman, David J. and John M. Moore
Pages
453-462
Year
Volume
20
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
METHYLMERCURY CHLORIDE increased @ 1,3,9,27,90 ug Hg % abnormal survivors by day 18 of incubation versus controls Both Male and Female Embryo 80 eggs/group Toxicity Factor Datasets incubation day 3 Laboratory
METHYLMERCURY CHLORIDE decreased @ 27, 90 ug Hg embryo crown to rump length by day 18 of incubation versus controls Both Male and Female Embryo 80 eggs/group Toxicity Factor Datasets incubation day 3 Laboratory
METHYLMERCURY CHLORIDE decreased @ 9, 27, 90 ug Hg % survival by day 18 of incubation versus controls Both Male and Female Embryo 80 eggs/group Toxicity Factor Datasets incubation day 3 Laboratory
Citation:

Genetic response of mallards to toxic effects of methyl mercuric chloride

Author(s)
Prince, H.H.
Pages
31-40
Publisher
American Society for Testing and Materials
Year
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
METHYLMERCURY CHLORIDE decreased hatchability versus controls Not Reported Juvenile 29 pairs Toxicity Factor Datasets Laboratory
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