LEPTOPHOS
Mallard duck (Anas platyrhynchos)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEPTOPHOS | decreased @ 260 ppm | body weight growth compared with controls | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| LEPTOPHOS | 5/5 @ 260 ppm | incidence of ataxia | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| LEPTOPHOS | 4/5 @ 260 ppm | incidence of CNS lesions | Both Male and Female | Juvenile | 3-5/group | Toxicity Factor Datasets | 14 d | Laboratory |
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab |
|---|---|---|---|---|---|---|---|---|---|
| LEPTOPHOS | decreased @ 270, 540 ppm | body weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | increased @ all doses | incidence of CNS lesions (demyelination, axonal degeneration in spinal cord) compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ 270 ppm | brain weight compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ all doses | activity of brain and plasma cholinesterase, and brain neurotoxic esterase compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory | |
| LEPTOPHOS | decreased @ 60, 270 ppm | plasma alkaline phosphatase activity compared with controls | Female | Juvenile | 6/group | Toxicity Factor Datasets | 20 wks | Laboratory |
