DICOFOL

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Displaying 20 data points

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Countries
DICOFOL 8.9 ± 20.26 ng/g ww Liver concentration NR Juvenile 64 SE coast Toxicity Factor Datasets BRAZIL
DICOFOL 81.7 ± 325.38 ng/g ww Fat concentration NR Juvenile 64 SE coast Toxicity Factor Datasets BRAZIL

Pacific Green Turtle (Chelonia mydas)

Citation:
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Countries
DICOFOL 81.7 ± 325.38 ng/g ww Fat concentration Not Reported Juvenile 64 SE coast Toxicity Factor Datasets BRAZIL
DICOFOL 8.9 ± 20.26 ng/g ww Liver concentration Not Reported Juvenile 64 SE coast Toxicity Factor Datasets BRAZIL

American Kestrel (Falco sparverius)

Citation:

Reproductive and morphological effects of o,p-dicofol on two generations of captive American kestrels

Author(s)
MacLellan, K.N.M., D.M. Bird, D.M. Fry, and J.L. Cowles
Pages
364-372
Year
Volume
30
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
DICOFOL increased @ 5 mg/kg bw incidence of abnormal gonads in male offspring of dicofol-treated females versus controls Male Adult 10/group Toxicity Factor Datasets Laboratory
DICOFOL decreased 5.45% (@ 5 mg/kg), 10.98% (@ 20 mg/kg) eggshell thickness compared to controls Female Adult 10/group Toxicity Factor Datasets Laboratory
DICOFOL non-detectable (@ 5 mg/kg), 560 ng/g (@ 20 mg/kg) mean concentration of metabolite dichlorobenzophenone in eggs Female Adult 10/group Toxicity Factor Datasets Laboratory
DICOFOL increased @ 5 and 20 mg/kg incidence of abnormal embyronic gonads Both Male and Female Embryo 10/group Toxicity Factor Datasets Laboratory
DICOFOL increased @ 5 mg/kg numbers of chicks or eggs lost (destroyed) by breeding male and female offspring of dicofol-treated females versus controls Female Adult 10/group Toxicity Factor Datasets Laboratory
DICOFOL no effect eggshell thickness for breeding female offspring of dicofol-treated females versus controls Female Adult 10/group Toxicity Factor Datasets Laboratory
Citation:

Behavior of captive American kestrels hatched from o,p-dicofol exposed females

Author(s)
MacLellan, K.N.M., D.M. Bird, L.J. Shutt, and D.M. Fry
Pages
411-415
Year
Volume
32
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
DICOFOL increased incidence of abnormal behavior in adult offspring of treated females Both Male and Female Adult 10 pairs/group Toxicity Factor Datasets Laboratory
Citation:

Metabolism and storage of p,p' dicofol

Author(s)
Schwarzbach, S.E., D. Michael Fry, B.E. Rosson and David M. Bird
Pages
206-210
Year
Volume
20
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
DICOFOL 8.11 (fat), 0.28 (liver) ug/g @ 0.3 mg/kg bw/d sum of geometric mean tissue concentrations (wet wt) of dicofol and metabolites (dichlorobenzophenone, mono-dechlorinated dicofol, dichlorobenzhydrol, DDE) Female Adult 2-4/group Toxicity Factor Datasets Laboratory
DICOFOL 82.36 (fat), 4.93 (liver), 1.15 (brain), 0.84 (oviduct) ug/g @ 3.0 mg/kg bw/d sum of geometric mean tissue concentrations (wet wt) of dicofol and metabolites (dichlorobenzophenone, mono-dechlorinated dicofol, dichlorobenzhydrol, DDE) Female Adult 2-4/group Toxicity Factor Datasets Laboratory

Mallard duck (Anas platyrhynchos)

Citation:

Effects of dicofol on mallard eggshell quality

Author(s)
Bennett, Jewel K., Stephen E. Dominguez and William L. Griffis
Pages
907-912
Year
Volume
19
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
DICOFOL increase @ 100 ug/g incidence of cracked and soft shelled eggs Female Adult 4-8/dose Toxicity Factor Datasets Laboratory
DICOFOL no effect egg production during study period Female Adult 4-8/dose Toxicity Factor Datasets Laboratory
DICOFOL no effect body weight at end of study Female Adult 4-8/dose Toxicity Factor Datasets Laboratory
DICOFOL no effect mean daily food consumption rate (169.8 g food/kg body weight) Female Adult 4-8/dose Toxicity Factor Datasets Laboratory
DICOFOL 2-12% decrease @ 10-100 ug/g eggshell thickness, compared to controls Female Adult 4-8/dose Toxicity Factor Datasets Laboratory
DICOFOL 5.4 (0.3 SE) ug/g wet wt. @ 3 ug/g diet; 18.1 (1.2 SE) @ 10 ug/g diet; 37.1 (1.6 SE) @ 30 ug/g diet; 150.7 (9.9SE) @ 100 ug/g diet, mean egg yolk concentrations of p,p'-dicofol after 37-42 d on dicofol diet Female Adult 4-8/dose Toxicity Factor Datasets Laboratory
DICOFOL ST = 1.020 - 0.056C regression equation relating shell thickness (mm) to log10 yolk concentration (C, ug/g); r2=0.39 Female Adult 100 Toxicity Factor Datasets Laboratory
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