CHLORPYRIFOS
Amphibians, Frogs and toads (Anura), Foothill Yellow-Legged Frog (Rana boylii)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties | Countries | 
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | Increased | Time to metamorphosis | B | Tadpole | 18/treatment | Eggs from Soda Creek | Toxicity Factor Datasets | Lake | USA | 
| CHLORPYRIFOS | Decreased | Cholinesterase activity | B | Tadpole | 18/treatment | Eggs from Soda Creek | Toxicity Factor Datasets | Lake | USA | 
| CHLORPYRIFOS | Logistic: 108.7 ug/L; SK: 66.5 ug/L | LC50 | B | Tadpole | 18/treatment | Eggs from Soda Creek | Toxicity Factor Datasets | Lake | USA | 
| CHLORPYRIFOS | No effect 0-14 d; various by 54 d; see size by exposure in Table 2 | Body mass | B | Tadpole | 18/treatment | Eggs from Soda Creek | Toxicity Factor Datasets | Lake | USA | 
| CHLORPYRIFOS | No effect 0-14 d; decrease by 34 d; see size by exposure in Table 2 | Snout-vent length | B | Tadpole | 18/treatment | Eggs from Soda Creek | Toxicity Factor Datasets | Lake | USA | 
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties | Countries | 
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | 3.005 mg/L | Mortality | B | Tadpole | See Table 1 | Eggs from stream near Fort Bragg | Toxicity Factor Datasets | Mendocino | USA | 
| CHLORPYRIFOS | See Figure 1 | Cholinesterase activity | B | Tadpole | See Table 1 | Eggs from stream near Fort Bragg | Toxicity Factor Datasets | Mendocino | USA | 
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | California Counties | Countries | Lab | 
|---|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | Alaska: NR, California: 53.6 ng/g lw | Blood concentration | B | Pup | Alaska: 3, California: 5 | Alaksa: 3 sites in eastern AK, California: 3 sites between Santa Cruz and Monterey | Toxicity Factor Datasets | |||
| CHLORPYRIFOS | Decreased | Survival | NR | Juvenile | 60 | University of Pittsburgh | Toxicity Factor Datasets | Lab | USA | |
| CHLORPYRIFOS | Decreased | Survival | NR | Tadpole | 60 | University of Pittsburgh | Toxicity Factor Datasets | Lab | USA | Laboratory | 
| CHLORPYRIFOS | Alaska: NR, California: 39.2 ng/g lw | Blood concentration | B | Juvenile | Alaska: 14, California: 6 | Alaksa: 3 sites in eastern AK, California: 3 sites between Santa Cruz and Monterey | Toxicity Factor Datasets | |||
| CHLORPYRIFOS | Alaska: NR, California: 43.8 ng/g lw | Blood concentration | F | Adult | Alaska: 38, California: 18 | Alaksa: 3 sites in eastern AK, California: 3 sites between Santa Cruz and Monterey | Toxicity Factor Datasets | |||
| CHLORPYRIFOS | Alaska: NR, California: 26.7 ng/g lw | Blood concentration | M | Adult | Alaska: 16, California: 11 | Alaksa: 3 sites in eastern AK, California: 3 sites between Santa Cruz and Monterey | Toxicity Factor Datasets | 
Mallard duck (Anas platyrhynchos)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab | 
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | 50.4 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 30 days | Laboratory | |
| CHLORPYRIFOS | 83.3 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 6 mos | Laboratory | |
| CHLORPYRIFOS | 145 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 36 hours | Laboratory | |
| CHLORPYRIFOS | 29.4 mg/kg | LD50 | Both Male and Female | Juvenile | 5 | Toxicity Factor Datasets | 7 days | Laboratory | 
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab | 
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | decreased | body weight compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory | |
| CHLORPYRIFOS | decreased | brain acetylcholinesterase activity compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory | |
| CHLORPYRIFOS | decreased | number of eggs produced, egg weight, eggshell thickness compared to controls | Both Male and Female | Adult | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory | |
| CHLORPYRIFOS | no effect | fertility and hatchability of eggs, and duckling survival to 14 days | Not Reported | Juvenile | 24 pairs/dose | Toxicity Factor Datasets | 7 and 11 months old | Laboratory | 
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Age-Specific | Lab | 
|---|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | 357 ppm | 11 day dietary LC50 | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| CHLORPYRIFOS | 236 ppm | 11 day dietary LC10 | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| CHLORPYRIFOS | 644 ppm (declining to 141 ppm over 11 d) | 5 day dietary LC50, when 5 day residue half life was simulated | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| CHLORPYRIFOS | decreased @ all doses | food consumption compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | |
| CHLORPYRIFOS | decreased @ all doses | body weight compared with controls | Not Reported | Juvenile | 10/group | Toxicity Factor Datasets | 14 d | Laboratory | 
Western Toad (Anaxyrus boreas formerly Bufo boreas)
| Chemical | Endpoint Value | Endpoint Description | Sex | Life Cycle Stage | Sample Size | Location | Type | Lab | 
|---|---|---|---|---|---|---|---|---|
| CHLORPYRIFOS | decrease @ 30 and 60 ppb | temperature tolerance, estimated by heating water at 1C/3min and using onset of spasms in frogs as the endpoint | Not Reported | Juvenile | 10 animals/replicate; 2 replicates/dose | Toxicity Factor Datasets | Laboratory |