CADMIUM CHLORIDE

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Mallard duck (Anas platyrhynchos)

Citation:

Effects of cadmium and lead ingestion on tissue concentrations of cadmium, lead, copper, and zinc in mallard ducks

Author(s)
Di Giulio, Richard T. and Patrick F. Scanlon
Pages
103-110
Year
Volume
39
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE, LEAD CHLORIDE 67.8 (12.4) @ 10 ppm Cd; 371.8 (22.3) @ 100 ppm Cd; 3.4 (0.6) @ 100 ppm Pb; 201.0 (26.9) @ 50 ppm Cd + 50 ppm Pb (ug/g, dry wt) mean (SE) Cd concentrations in kidney Male Juvenile 6-8 birds/dose Toxicity Factor Datasets 128 d (at initiation) Laboratory
CADMIUM CHLORIDE, LEAD CHLORIDE 4.1 (0.5) @ 10 ppm Pb; 22.5 (1.5) @ 100 ppm Pb; 3.1 (0.3) @ 5 ppm Cd + 5 ppm Pb; 16.1 (1.4) @ 50 ppm Cd+ 50 ppm Pb (ug/g, dry wt) mean (SE) Pb concentrations in kidney Male Juvenile 6-8 birds/dose Toxicity Factor Datasets 128 d (at initiation) Laboratory
CADMIUM CHLORIDE, COPPER COMPOUNDS, LEAD CHLORIDE 56.7(7.7) @ 100 ppm Cd; 37.7 (3.7) @ 50 ppm Cd + 50 ppm Pb (ug/g, dry wt) mean (SE) Cu concentrations (ug/g, dry wt) in kidney Male Juvenile 6-8 birds/dose Toxicity Factor Datasets 128 d (at initiation) Laboratory
CADMIUM CHLORIDE, LEAD CHLORIDE, ZINC COMPOUNDS 99 (6) @ 110 ppm Cd; 125 (7) @ 100 ppm Cd; 100 (5) @ 5 ppm Cd + 5 ppm Pb; 112 (2) @ 50 ppm Cd + 50 ppm Pb mean (SE) Zn concentrations (ug/g, dry wt) in kidney Male Juvenile 6-8 birds/dose Toxicity Factor Datasets 128 d (at initiation) Laboratory
CADMIUM CHLORIDE, LEAD CHLORIDE 7.2 (0.9) ug Pb/g @ 100 ppm Pb; 104.8 (19.1) ug Pb/g @ 100 ppm Cd; 54.2 (3.7) ug Cd/g @ 50 ppm Cd + 50 ppm Pb (dry wt) mean (SE) concentrations in liver Male Juvenile 6-8 birds/dose Toxicity Factor Datasets 128 d (at initiation) Laboratory
Citation:

Uptake and retention of dietary cadmium in mallard ducks

Author(s)
White, Donald H. and Mack T. Finley
Pages
53-59
Year
Volume
17
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE decreased @ all doses/30 d post-treatment, and 200 ppm/90 d of treatment mean testis weight versus controls Male Adult 5 testes/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE no effect mortality versus controls Both Male and Female Adult 20 pairs/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE no effect body wt, hematocrit, hemoglobin, food consumption versus controls Both Male and Female Adult 20 pairs/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE 2.116 (@ 2 ppm), 19.510 (@ 20 ppm), 96.600 9@ 200 ppm) ppm, wet wt mean Cd concentrations in liver after 90 d of treatment Both Male and Female Adult 20 pairs/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE 4.627 (@ 2 ppm), 54.333 (@ 20 ppm), 77.222 (@ 200 ppm) ppm, wet wt mean Cd concentrations in kidneys after 90 d of treatment Both Male and Female Adult 20 pairs/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE increased to 0.010 (@ 20 ppm), 0.040 (@ 200 ppm) ppm, wet wt Cd concentrations in eggs versus controls Both Male and Female Adult 15 eggs (20 ppm), 3 eggs (200 ppm) Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE increased @ 200 ppm/60 or 90 d of treatment, 30 d post-treatment mean kidney weight versus controls Both Male and Female Adult 10 kidneys/group Toxicity Factor Datasets 1 yr Laboratory
Citation:

Sublethal effects of cadmium ingestion on mallard ducks

Author(s)
Di Giulio, Richard T. and Patrick F. Scanlon
Pages
765-771
Year
Volume
13
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE decreased @ 450 ppm body and liver weights compared to controls Not Reported Adult 12 birds/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE increased @ 150, 450 ppm kidney and adrenal weights compared to controls Not Reported Adult 12 birds/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE increased @ 450 ppm plasma uric acid, adrenal corticosterone levels Not Reported Adult 12 birds/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE no effect food consumption compared to controls Not Reported Adult 12 birds/group Toxicity Factor Datasets 1 yr Laboratory
CADMIUM CHLORIDE decreased @ 450 ppm liver aldolase activity, plasma triiodothyronine levels Not Reported Adult 12 birds/group Toxicity Factor Datasets 1 yr Laboratory
Citation:

Effects of cadmium ingestion and food restriction on energy metabolism and tissue metal concentrations in mallard ducks (Anas platyrhynchos)

Author(s)
Di Giulio, R.T. and P.F. Scanlon
Pages
433-444
Year
Volume
37
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE increased @ 10, 50 ug/g diet kidney Cu concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE increased @ 10, 50 ug/g diet kidney Zn concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect BW versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect brain, liver, kidney, testes weights versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect liver glycogen concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect % packed cell volume versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect plasma glucose, NEFA, urea, or uric acid versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect thyroid hormone concentrations versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect adrenal wt, corticosterone concentrations versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE increased @ 10, 50 ug/g diet liver cadmium concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect liver Cu concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE no effect liver Zn concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
CADMIUM CHLORIDE increased @ 10, 50 ug/g diet kidney Cd concentration versus controls Male Adult 8 Toxicity Factor Datasets 32 weeks Laboratory
Citation:

Histopathologic efffects of dietary cadmium on kidneys and testes of mallard ducks

Author(s)
White, Donald H., Mack T. Finley and John F. Ferrell
Pages
551-558
Year
Volume
4
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Age-Specific Lab
CADMIUM CHLORIDE increased @ 200 ppm weight of kidneys versus controls Both Male and Female Adult 10 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE decreased @ 200 ppm weight of testes versus controls Male Adult 5 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE increased @ 200 ppm incidence of kidney lesions versus controls Both Male and Female Adult 10 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE increased @ 200 ppm incidence of testes alterations (atrophy, decreased spermatogenesis) versus controls Male Adult 5 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE 0.46 (@ 0 ppm), 4.63 (@ 2 ppm), 54.33 (@ 20 ppm), 77.22 (@ 200 ppm) ppm, wet wt mean Cd concentrations in kidneys (ppm, wet wt) by 90 days Both Male and Female Adult 10 birds Toxicity Factor Datasets first year Laboratory
CADMIUM CHLORIDE 0.03 (@ 0 ppm), 0.02 (@ 2 ppm), 0.72 (@ 20 ppm) 8.47 (@ 200 ppm) ppm, wet wt mean Cd concentrations in testes (ppm, wet wt) by 90 days Male Adult 5 birds Toxicity Factor Datasets first year Laboratory
Citation:

Effects of dietary cadmium on mallard ducklings

Author(s)
Cain, Brian W., Lou Sileo, J. Christian Franson and John Moore
Pages
286-297
Year
Volume
32
Chemical Endpoint Value Endpoint Description Sex Life Cycle Stage Sample Size Location Type Lab
CADMIUM CHLORIDE decreased @ 20 ppm packed cell volume and hemoglobin concentration by 8 wks of treatment compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
CADMIUM CHLORIDE increased @ 20 ppm incidence of kidney lesions by 12 wks of treatment compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
CADMIUM CHLORIDE increased @ 20 ppm serum glutamic pyruvic transaminase activity by 8 wks of treatment compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
CADMIUM CHLORIDE 0.10 (@ 0 ppm), 10.13 (@ 5 ppm), 16.25 (@ 10 ppm), 42.21 (@ 20 ppm) ppm, wet wt mean Cd concentrations in liver by 12 wks of treatment Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
CADMIUM CHLORIDE no effect body weight, liver weight, and femur density compared to controls Not Reported Juvenile 12 birds per timexdose treatment day old Toxicity Factor Datasets Laboratory
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